Jaskille Amín D, Ramella-Roman Jessica C, Shupp Jeffrey W, Jordan Marion H, Jeng James C
The Burn Center, Department of Surgery, Washington Hospital Center, Washington, DC 20010, USA.
J Burn Care Res. 2010 Jan-Feb;31(1):151-7. doi: 10.1097/BCR.0b013e3181c7ed60.
The judgment of which wounds are expected to heal within 21 days is one of the most difficult and important tasks of the burn surgeon. The quoted accuracy of 64 to 76% by senior burn surgeons underscores the importance of an adjunct technology to help make this determination. A plethora of techniques have been developed in the last 70 years. Laser Doppler imaging (LDI) is one of the most recent and widely studied of these techniques. The technology provides an estimate of perfusion through the burn wound, the assumption being that a lower perfusion correlates with a deeper wound and, therefore, a longer time to heal. Although some reports suggest accuracy between 96 and 100% and that it does this 2 days ahead of clinical judgment, others have questioned its applicability to clinical practice. This article, the second of a two-part series, has two objectives: 1) a review of the Doppler principle and how the LDI uses it to estimate perfusion; and 2) a critical assessment of the burn literature on the LDI. Part I provides a historical perspective of the different technologies used through the last 70 years to assist in the determination of burn depth. Laser Doppler has brought technology closer to provide a reliable adjuvant to the clinical prediction of healing, yet, caution is warranted. A clear understanding of the limitations of LDI is needed to put the current research in perspective to find the right clinical application for LDI.
判断哪些伤口有望在21天内愈合是烧伤外科医生最困难且重要的任务之一。资深烧伤外科医生所引用的64%至76%的准确率凸显了辅助技术对于做出这一判断的重要性。在过去70年里已开发出大量技术。激光多普勒成像(LDI)是这些技术中最新且研究广泛的技术之一。该技术可估算烧伤创面的灌注情况,其假设是较低的灌注与较深的伤口相关,因此愈合时间更长。尽管一些报告表明其准确率在96%至100%之间,且能比临床判断提前2天做出判断,但也有人质疑其在临床实践中的适用性。本文是系列文章的第二篇,有两个目的:1)回顾多普勒原理以及LDI如何利用该原理估算灌注;2)对关于LDI的烧伤文献进行批判性评估。第一篇文章提供了过去70年用于辅助判断烧伤深度的不同技术的历史视角。激光多普勒已使技术更接近为愈合的临床预测提供可靠辅助,但仍需谨慎。需要清楚了解LDI的局限性,以便正确看待当前研究,为LDI找到合适的临床应用。