噬血细胞综合征患者淋巴结中浆细胞显著增多：一例报告
Plasma cells increased markedly in lymph node in hemophagocytic syndrome: a case report.
作者信息
Congyang Li, Xuexin Hu, Hao Li, Chunge Li, Yingye Miao
机构信息
Department of Pathology, People's Liberation Army 152 hospital, Pingdingshan City, Henan province, PR China.
出版信息
Cases J. 2009 Nov 27;2:9096. doi: 10.1186/1757-1626-2-9096.
INTRODUCTION
Hemophagocytic syndrome is a rare clinicopathological condition characterized by the activation of the mononuclear phagocyte system, resulting in hemophagocytosis in the reticuloendothelial systems. The pathogenesis of HPS remains unclear.
CASE PRESENTATION
We report the case of a 20-year-old soldier suffering from HPS. Because of long history fever and no reasons being found, his left groin lymph node and left neck lymph node biopsy were done with two weeks interval. We found a marked increase in plasma cells in left neck lymph node during the course of the disease.
CONCLUSION
Our result provides a new thought for the researchers to understand the mechanisms responsible for the phagocytosis in HPS.
引言
噬血细胞综合征是一种罕见的临床病理状况，其特征为单核吞噬细胞系统激活，导致网状内皮系统出现噬血细胞现象。噬血细胞综合征的发病机制仍不清楚。
病例报告
我们报告一例20岁患噬血细胞综合征的士兵病例。因长期发热且病因不明，在两周的间隔时间内对其左腹股沟淋巴结和左颈部淋巴结进行了活检。在病程中我们发现左颈部淋巴结浆细胞显著增多。
结论
我们的结果为研究人员理解噬血细胞综合征中吞噬作用的机制提供了新的思路。
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