Taneous Mary, Ramalingam Preetha, Mode Donald G, Heiner Jared G, Terris Martha K, Lee Jeffrey R
Section of Pathology, Augusta Veterans Affairs Medical Center, 1 Freedom Way, Augusta, GA 30904, USA.
J Med Case Rep. 2009 Nov 30;3:9306. doi: 10.1186/1752-1947-3-9306.
Malignancies are rare in defunctionalized bladders and are thought to arise from metaplasia secondary to chronic inflammation. Transitional cell and squamous cell carcinomas are the most common but there are three reported cases of mucinous adenocarcinoma.
We report a 57-year-old Caucasian man presenting with penile discharge for 30 years following ileal conduit surgery for neurogenic bladder, and who was found to have primary mucinous adenocarcinoma of his defunctionalized bladder.
Although urinary diversion without cystectomy is less common in current urologic practice, there are many patients with longstanding defunctionalized bladders. While there are no established surveillance protocols, defunctionalized bladder patients with urethral discharge should be evaluated.
功能失用性膀胱的恶性肿瘤较为罕见,被认为是由慢性炎症继发化生引起的。移行细胞癌和鳞状细胞癌最为常见,但有三例黏液性腺癌的报道。
我们报告了一名57岁的白种男性,在因神经源性膀胱接受回肠代膀胱手术后出现阴茎溢液30年,被发现患有功能失用性膀胱原发性黏液性腺癌。
尽管在当前泌尿外科实践中,不进行膀胱切除术的尿流改道较少见,但有许多长期存在功能失用性膀胱的患者。虽然没有既定的监测方案,但对有尿道溢液的功能失用性膀胱患者应进行评估。