Ramesh Balasundaram, Shetty Sanathkumar, Bastawrous Salah S
Department of Trauma and Orthopaedics, Glan Clwyd Hospital, Sarn Lane, Bodelwyddan, Rhyl, North Wales, LL18 5UJ, UK.
J Med Case Rep. 2009 Nov 13;3:121. doi: 10.1186/1752-1947-3-121.
Pigmented villonodular synovitis is a disease which affects the synovial joints and tendon sheaths. Although the exact aetiological factors are not known, we believe that recurrent haemarthrosis has a role in the aetiology of this condition.
A 62-year-old Caucasian man presented with gradually worsening pain and stiffness in his right knee. The patient was on anticoagulation therapy and had been treated for recurrent episodes of spontaneous haemarthrosis of the knee. The International Normalized Ratio on each occasion suggested poor control of the anticoagulation therapy. A diagnosis of pigmented villonodular synovitis was made based on intra-operative findings and was further confirmed by a histopathological examination.
This report is presented to highlight the unusual association of haemarthrosis and pigmented villonodular synovitis.
色素沉着绒毛结节性滑膜炎是一种影响滑膜关节和腱鞘的疾病。尽管确切的病因尚不清楚,但我们认为反复关节积血在该疾病的病因中起作用。
一名62岁的白种男性因右膝疼痛和僵硬逐渐加重前来就诊。该患者正在接受抗凝治疗,并且曾因膝关节反复自发性关节积血接受治疗。每次的国际标准化比值提示抗凝治疗控制不佳。根据术中发现诊断为色素沉着绒毛结节性滑膜炎,并通过组织病理学检查进一步证实。
本报告旨在强调关节积血与色素沉着绒毛结节性滑膜炎之间的罕见关联。