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口服抗凝治疗患者的膝关节色素沉着绒毛结节性滑膜炎:一例报告

Pigmented villonodular synovitis of the knee in a patient on oral anticoagulation therapy: a case report.

作者信息

Ramesh Balasundaram, Shetty Sanathkumar, Bastawrous Salah S

机构信息

Department of Trauma and Orthopaedics, Glan Clwyd Hospital, Sarn Lane, Bodelwyddan, Rhyl, North Wales, LL18 5UJ, UK.

出版信息

J Med Case Rep. 2009 Nov 13;3:121. doi: 10.1186/1752-1947-3-121.

DOI:10.1186/1752-1947-3-121
PMID:20062764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2803798/
Abstract

INTRODUCTION

Pigmented villonodular synovitis is a disease which affects the synovial joints and tendon sheaths. Although the exact aetiological factors are not known, we believe that recurrent haemarthrosis has a role in the aetiology of this condition.

CASE PRESENTATION

A 62-year-old Caucasian man presented with gradually worsening pain and stiffness in his right knee. The patient was on anticoagulation therapy and had been treated for recurrent episodes of spontaneous haemarthrosis of the knee. The International Normalized Ratio on each occasion suggested poor control of the anticoagulation therapy. A diagnosis of pigmented villonodular synovitis was made based on intra-operative findings and was further confirmed by a histopathological examination.

CONCLUSION

This report is presented to highlight the unusual association of haemarthrosis and pigmented villonodular synovitis.

摘要

引言

色素沉着绒毛结节性滑膜炎是一种影响滑膜关节和腱鞘的疾病。尽管确切的病因尚不清楚,但我们认为反复关节积血在该疾病的病因中起作用。

病例报告

一名62岁的白种男性因右膝疼痛和僵硬逐渐加重前来就诊。该患者正在接受抗凝治疗,并且曾因膝关节反复自发性关节积血接受治疗。每次的国际标准化比值提示抗凝治疗控制不佳。根据术中发现诊断为色素沉着绒毛结节性滑膜炎,并通过组织病理学检查进一步证实。

结论

本报告旨在强调关节积血与色素沉着绒毛结节性滑膜炎之间的罕见关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f571/2803798/1d3d6f353544/1752-1947-3-121-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f571/2803798/cc60ee6f3785/1752-1947-3-121-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f571/2803798/1d3d6f353544/1752-1947-3-121-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f571/2803798/cc60ee6f3785/1752-1947-3-121-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f571/2803798/1d3d6f353544/1752-1947-3-121-2.jpg

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本文引用的文献

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Pigmented villonodular synovitis of the ankle occurring in a patient on anticoagulation therapy.一名正在接受抗凝治疗的患者发生了踝关节色素沉着绒毛结节性滑膜炎。
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Successful arthroscopic treatment of pigmented villonodular synovitis of the knee in a patient with congenital deficiency of plasminogen activator inhibitor-1 and recurrent haemarthrosis.成功对一名患有纤溶酶原激活物抑制剂-1先天性缺乏症并反复发生关节积血的患者进行膝关节色素沉着绒毛结节性滑膜炎的关节镜治疗。
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色素沉着绒毛结节性滑膜炎和腱鞘炎:166例临床流行病学研究及文献复习
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Pigmented villonodular synovitis: light and electron microscopic studies.
Semin Arthritis Rheum. 1982 Aug;12(1):32-43. doi: 10.1016/0049-0172(82)90021-x.
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Pigmented villonodular synovitis in multiple joints. Occurrence in a child with cavernous haemangioma of lip and pulmonary stenosis.多关节色素沉着绒毛结节性滑膜炎。发生于一名患有唇部海绵状血管瘤和肺动脉狭窄的儿童。
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