Department of Internal Medicine, Division of Rheumatology, Washington University, Saint Louis, MO 63110, USA.
Immunity. 2009 Dec 18;31(6):852-3. doi: 10.1016/j.immuni.2009.11.006.
In this issue of Immunity, reports by Long et al. (2009) and Ruan et al. (2009) suggest that the transcription factor NF-kappaB-c-Rel is an important molecular mechanism by which T cell receptor-specificity for self-antigens instructs the selection of Foxp3(+) regulatory T cells.
本期《免疫》发表了龙等（2009）和阮等（2009）的报告，提示转录因子 NF-κB-c-Rel 是 T 细胞受体对自身抗原的特异性如何指导 Foxp3(+)调节性 T 细胞选择的一个重要分子机制。
