Department of Biochemistry and Molecular Biology, The University of Texas Medical School, Houston, 77030, USA.
Mol Cell. 2009 Dec 25;36(6):920-1. doi: 10.1016/j.molcel.2009.12.013.
In this issue of Molecular Cell, Fukao et al. (2009) report that HuD upregulates mRNA translation through direct interaction with eIF4A in the 5' cap-binding complex, revealing a posttranscriptional role for HuD in neuronal development and plasticity.
本期《分子细胞》杂志中,Fukao 等人(2009 年)报道 HuD 通过与 5' 帽结合复合物中的 eIF4A 直接相互作用而上调 mRNA 翻译,揭示了 HuD 在神经元发育和可塑性中的转录后作用。