Erickson J D
Birth Defects and Genetic Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333.
Teratology. 1991 Jan;43(1):41-51. doi: 10.1002/tera.1420430106.
The Atlanta Birth Defects Case-Control Study data comprises information obtained from interviews with parents of 4,900 babies born with major birth defects and with the parents of 3,000 babies born without defects. The source of cases is the Centers for Disease Control's Metropolitan Atlanta Congenital Defects program; the case-control study is population-based. Birth defects are classified into 92 groups and cross-tabulated by 105 exposure/risk factor variables; data from selected cross-tabulations are presented. The associations of each of the 105 exposure variables with all types of defects combined are presented, as are the associations of each of the 92 defect groups with the specific exposure variable, maternal diabetes. These data can be used to evaluate hypotheses arising from other sources, and for the purpose of "generating" hypotheses. The data describing all 92 x 105 cross-tabulations are available to other investigators on floppy disk; write to Chief, Birth Defects and Genetic Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333.
亚特兰大出生缺陷病例对照研究数据包含从对4900名患有主要出生缺陷婴儿的父母以及3000名无缺陷婴儿的父母的访谈中获得的信息。病例来源是疾病控制中心的亚特兰大大都会先天性缺陷项目;该病例对照研究是以人群为基础的。出生缺陷被分为92组,并按105个暴露/风险因素变量进行交叉列表;呈现了选定交叉列表的数据。列出了105个暴露变量中的每一个与所有类型缺陷综合起来的关联,以及92个缺陷组中的每一个与特定暴露变量——母亲糖尿病的关联。这些数据可用于评估其他来源产生的假设,以及用于“生成”假设的目的。描述所有92×105交叉列表的数据可通过软盘提供给其他研究人员;写信至佐治亚州亚特兰大市疾病控制中心出生缺陷与遗传疾病科科长,邮编30333。