Maki Kara L, Braun Richard J, Henshaw William D, King-Smith P Ewen
Department of Mathematical Sciences, University of Delaware, Newark, DE 19711, USA.
Math Med Biol. 2010 Sep;27(3):227-54. doi: 10.1093/imammb/dqp023. Epub 2010 Jan 11.
We study the relaxation of a model for the human tear film after a blink on a stationary eye-shaped domain corresponding to a fully open eye using lubrication theory and explore the effects of viscosity, surface tension, gravity and boundary conditions that specify the pressure. The governing non-linear partial differential equation is solved on an overset grid by a method of lines using a finite-difference discretization in space and an adaptive second-order backward-difference formula solver in time. Our 2D simulations are calculated in the Overture computational framework. The computed flows show sensitivity to both our choices between two different pressure boundary conditions and the presence of gravity; this is particularly true around the boundary. The simulations recover features seen in 1D simulations and capture some experimental observations including hydraulic connectivity around the lid margins.
我们使用润滑理论研究了在对应于完全睁开眼睛的固定眼形区域上眨眼后人眼泪膜模型的松弛过程,并探讨了粘度、表面张力、重力以及指定压力的边界条件的影响。通过线方法在重叠网格上求解控制非线性偏微分方程,在空间上使用有限差分离散化,在时间上使用自适应二阶向后差分公式求解器。我们的二维模拟是在Overture计算框架中进行的。计算得到的流动对我们在两种不同压力边界条件之间的选择以及重力的存在都表现出敏感性;在边界附近尤其如此。模拟恢复了一维模拟中看到的特征,并捕捉了一些实验观察结果,包括眼睑边缘周围的水力连通性。