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[根治性前列腺切除术后尿失禁:手术技术的历史演变及当前功能结局]

[Urinary incontinence after radical prostatectomy: surgical technique historic evolution and present functional outcomes].

作者信息

Delgado Oliva Francisco José, Caballero Romeo Juan Pablo, García Serrado Diego, Prieto Chaparro Luis, Carro Rubias Carlos, Chillón Sempere Silvia, De Paz Cruz Lucas, De Nova Sánchez Ernesto

机构信息

Servicio de Urología, Hospital General Universitario Elche, Elche, Alicante, España.

出版信息

Arch Esp Urol. 2009 Dec;62(10):809-18. doi: 10.4321/s0004-06142009001000005.

Abstract

OBJECTIVES

In patients with localized prostate cancer and life expectancy longer than 10 years, radical prostatectomy (RP) remains the Gold Standard. Radical surgery must achieve good oncological and functional outcomes with early continence and potency. In expert hands RP offers very low post-prostatectomy urinary incontinence rates. To analyze functional outcomes regarding urinary incontinence (UI) after RP in our centre in the last ten years.

METHODS

We have performed a retrospective study of the 137 patients who had a radical prostatectomy (open retropubic or laparoscopic) on the General University Hospital of Elche from 1998 to 2008. Two patient groups were analyzed, patients who had surgery from 1998 to 2003, and those who had surgery from 2004 to 2008. Stress UI rates after RP were determined in both groups at 1, 3, 6 and 12 months following surgery with patient pad day usage. Urethrovesical anastomosis strictures were also analyzed in each group and their resolution.

RESULTS

15 patients were excluded from the initial 137 because cT3 stage was detected, remaining 122 prostatectomies with <cT2c stage in the study. Average age was 67 years (50-74). Mean preoperative PSA was 8.1 ng/ml (4.5-25). Biopsy Gleason score was < 6 in 70% (85/122) and 7-8 in 30 % (37/122). In the period between 1998 and 2003, 49 patients underwent surgery and results were: initially continent 28.5% (14/49), continent after one month: 6.1% (3/49), at 3 months: 12.2% (6/49), six months 8.1% ( 4/49) and at a year: 22.4%(11/49). 20.4% (10/49) remain with mild incontinence and moderate/severe 2% (1/49). In this period 78% of the patients remain continent and 22% incontinent. In the period 2004-2008, 73 radical prostatectomies were performed with the following continence rates: initial continence 44% (32/73), after one month 0 patients, 3 months 6.8 % (5/73), 6 months 12.3 % (9/73), a year later 24.6 % (18/73). Mild incontinence was observed in 8.2% ( 6/73) and moderate-severe in 4% (3/73). 88% of the patients achieved continence and 12% remain incontinent.

CONCLUSIONS

Urinary incontinence is a low frequency disorder in patients who undergo RP. Continence rates have been improving during the last years along with surgical technique and urologic expertise. Anti-incontinence devices after PR are rarely necessary and use is overrated.

摘要

目的

对于局限性前列腺癌且预期寿命超过10年的患者,根治性前列腺切除术(RP)仍是金标准。根治性手术必须在早期实现控尿和性功能恢复的良好肿瘤学及功能学结果。在专家手中,RP术后尿失禁发生率极低。分析过去十年我们中心RP术后尿失禁(UI)的功能学结果。

方法

我们对1998年至2008年在埃尔切大学总医院接受根治性前列腺切除术(开放耻骨后或腹腔镜手术)的137例患者进行了回顾性研究。分析了两个患者组,即1998年至2003年接受手术的患者以及2004年至2008年接受手术的患者。通过患者每日使用尿垫情况,在两组患者术后1、3、6和12个月时确定RP术后压力性UI发生率。还分析了每组患者的尿道膀胱吻合口狭窄情况及其解决情况。

结果

最初的137例患者中有15例因检测到cT3期被排除,研究中剩余122例<cT2c期前列腺切除术患者。平均年龄为67岁(50 - 74岁)。术前平均PSA为8.1 ng/ml(4.5 - 25)。活检Gleason评分<6分的占70%(85/122),7 - 8分的占30%(37/122)。在1998年至2003年期间,49例患者接受了手术,结果如下:初始控尿率为28.5%(14/49),术后1个月控尿率为6.1%(3/49),3个月时为12.2%(6/49),6个月时为8.1%(4/49),1年时为22.4%(11/49)。20.4%(10/49)患者仍有轻度尿失禁,2%(1/49)为中度/重度尿失禁。在此期间,78%的患者实现控尿,22%尿失禁。在2004 - 2008年期间,进行了73例根治性前列腺切除术,控尿率如下:初始控尿率为44%(32/73),术后1个月时0例患者控尿,3个月时为6.8%(5/73),6个月时为12.3%(9/73),1年后为24.6%(18/73)。观察到8.2%(6/73)患者有轻度尿失禁,4%(3/73)为中度/重度尿失禁。88%的患者实现控尿,12%尿失禁。

结论

尿失禁在接受RP的患者中是一种低发性疾病。在过去几年中,随着手术技术和泌尿外科专业知识的提高,控尿率一直在改善。RP术后很少需要使用抗尿失禁装置,且其使用被高估了。

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