Medical Radiological Research Center (MRRC), Koroliov str., 4, Obninsk, 249036, Russia.
Health Phys. 2010 Feb;98(2):345-51. doi: 10.1097/HP.0000348462.29306.59.
The aim of this investigation is to find out the optimal algorithm for mathematical processing of the EPR spectra of irradiated tooth enamel for estimating the amplitude of the radiation-induced signal, which is used for determination of the absorbed dose in enamel for retrospective individual dosimetry. A recently developed analytical model, which takes into account the line shape variation of the enamel EPR spectral components registered at different microwave power, was applied to spectra processing in various operation modes to simulate spectra processing techniques differing by the number of fitted parameters. The precision of dose determination at spectra processing was assessed by the root mean square deviation between experimental and nominal doses for sets of spectra of enamel samples irradiated in different doses and measured at different microwave power. It is shown that in the case of pooled enamel samples prepared as a mixture from different teeth, the higher precision of spectra processing is obtained using a model with fixed native background signal line shape (characterized by width and asymmetry parameters). In case of individual samples prepared each from a different tooth, better results are obtained using a model with variable background signal line shape.
本研究旨在寻找一种最优的数学算法,对受辐照牙釉质的 EPR 光谱进行处理,以估算辐射诱导信号的幅度,该信号用于确定牙釉质中的吸收剂量,以进行个体回顾剂量测定。最近开发的一种分析模型,考虑了在不同微波功率下记录的牙釉质 EPR 光谱分量的线形变化,应用于各种操作模式下的光谱处理,以模拟通过拟合参数数量不同的光谱处理技术。通过在不同剂量下辐照的牙釉质样本的光谱在不同微波功率下测量得到的实验剂量和名义剂量之间的均方根偏差来评估剂量测定的精度。结果表明,在混合自不同牙齿的牙釉质样本的情况下,使用具有固定本底信号线形(由宽度和不对称参数表征)的模型可以获得更高的光谱处理精度。对于每个牙齿单独制备的样本,使用具有可变背景信号线形的模型可以获得更好的结果。