Department of Obstetrics and Gynecology, Clinica Universitaria de Navarra, University of Navarra, Pamplona, Spain.
Ultrasound Obstet Gynecol. 2010 Feb;35(2):228-32. doi: 10.1002/uog.7535.
To assess whether the analysis of cyst content using mean gray value (MGV) can discriminate ovarian endometriomas from other unilocular ovarian cysts in premenopausal women.
Stored three-dimensional (3D) volumes from 54 unilocular ovarian cysts diagnosed in 50 premenopausal women (mean age, 37 (range, 22-50) years) were analyzed to calculate the MGV from cyst content. Cysts with solid components or septations were excluded. MGV was calculated in all cases with the Virtual Organ Computer-aided AnaLysis technique. The B-mode presumptive diagnosis based on the examiner's subjective impression was also recorded.
Sixteen of the cysts resolved spontaneously and were given a final clinical diagnosis of hemorrhagic functional cyst, while 38 cysts were removed surgically (diagnosed histologically as seven simple cysts, three hemorrhagic cysts, 20 endometriomas, five mucinous cysts and three paraovarian cysts). B-mode diagnoses were as follows: seven simple cysts, 18 hemorrhagic cysts, 24 endometriomas, three mucinous cysts and two paraovarian cysts. MGV was significantly higher in ovarian endometrioma when compared with all other kinds of cyst. The receiver-operating characteristics curve showed that using an MGV cut-off >or= 15.560 had a sensitivity of 85% and a specificity of 76.5% for diagnosing ovarian endometrioma (area under the curve, 0.831; 95% CI, 0.718-0.944). These figures were similar to those for B-mode diagnosis (sensitivity, 90%; specificity, 82%) (McNemar test, P = 1.000). Combining B-mode and MGV gave a sensitivity of 80% and a specificity of 91%.
Cyst content MGV is higher in ovarian endometrioma than it is in other unilocular ovarian cysts. The diagnostic performance of MGV is similar to that of the examiner's subjective impression. The combination of both criteria achieves the highest specificity.
评估使用平均灰度值（MGV）分析囊内容物是否可以区分绝经前妇女的卵巢子宫内膜异位囊肿与其他单房性卵巢囊肿。
对 50 名绝经前妇女（平均年龄 37 岁[范围 22-50 岁]）诊断的 54 个单房性卵巢囊肿的三维（3D）容积进行存储，以计算囊内容物的 MGV。排除具有实性成分或分隔的囊肿。所有病例均采用虚拟器官计算机辅助分析技术计算 MGV。还记录了基于检查者主观印象的 B 型模式假定诊断。
16 个囊肿自发消退，并最终临床诊断为出血性功能性囊肿，38 个囊肿通过手术切除（组织学诊断为 7 个单纯囊肿、3 个出血性囊肿、20 个子宫内膜异位囊肿、5 个黏液性囊肿和 3 个卵巢旁囊肿）。B 型诊断分别为：7 个单纯囊肿、18 个出血性囊肿、24 个子宫内膜异位囊肿、3 个黏液性囊肿和 2 个卵巢旁囊肿。与所有其他类型的囊肿相比，卵巢子宫内膜异位囊肿的 MGV 明显更高。受试者工作特征曲线显示，使用 MGV 截断值>或=15.560 诊断卵巢子宫内膜异位囊肿的敏感性为 85%，特异性为 76.5%（曲线下面积，0.831；95%CI，0.718-0.944）。这些数字与 B 型诊断相似（敏感性，90%；特异性，82%）（McNemar 检验，P=1.000）。将 B 型和 MGV 结合使用，敏感性为 80%，特异性为 91%。
卵巢子宫内膜异位囊肿的囊内容物 MGV 高于其他单房性卵巢囊肿。MGV 的诊断性能与检查者的主观印象相似。结合两者标准可达到最高的特异性。
