Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, 401 North Broadway, Suite 1440, Baltimore, MD 21231, USA.
Thorac Surg Clin. 2009 Aug;19(3):391-400. doi: 10.1016/j.thorsurg.2009.06.003.
This article has reviewed radiation treatment of thoracic malignancies in elderly patients. In general the literature suggests that thoracic irradiation is equally efficacious in elderly patients as in younger patients and is associated with increased but acceptable toxicity. Technical advances are allowing a further reduction in morbidity with preliminary results suggestive of stable outcomes. Prospective data from elderly specific trials are needed to determine the optimal treatment of lung cancer and to compare innovative radiation technology with standard therapies.
本文回顾了老年患者胸部恶性肿瘤的放射治疗。一般来说,文献表明,胸部放疗对老年患者与年轻患者同样有效,且相关毒性可接受。技术进步使发病率进一步降低,初步结果表明结局稳定。需要来自老年患者专项试验的前瞻性数据来确定肺癌的最佳治疗方法,并比较创新的放射技术与标准疗法。