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栓塞术对血管纤维瘤内镜切除术的影响。

Effect of embolisation on endoscopic resection of angiofibroma.

作者信息

Mohammadi M, Saedi B, Basam A

机构信息

ENT Research Center, Tehran University of Medical Sciences, Iran.

出版信息

J Laryngol Otol. 2010 Jun;124(6):631-5. doi: 10.1017/S0022215109992726. Epub 2010 Jan 13.

Abstract

OBJECTIVE

To determine the effect of embolisation on endoscopic resection of angiofibroma.

SUBJECTS AND METHOD

A partially blinded trial was undertaken. Twenty-three patients with angiofibroma (nine embolised and 14 not embolised) underwent endoscopic resection between January 2007 and August 2008 in two tertiary referral centres. Demographic data were collected, the pre-operative tumour extent was assessed by computed tomography, and tumours were staged according to their computed tomography appearance (Radkowski scale). In addition, we evaluated the duration of surgery, amount of haemorrhage, blood pressure during surgery, duration of hospitalisation, complications of surgery and embolisation, cost of treatment, and number of post-operative recurrences, as well as the angiographic characteristics in the embolisation group.

RESULTS

There was no significant difference between the general characteristics of both groups. At the end of the study period, we could find no significant difference between the two groups regarding haemorrhage, number of recurrences or complications. The only significant difference was cost of treatment, which was significantly higher in the embolisation group.

CONCLUSION

Endoscopic resection is a feasible and safe method for angiofibroma surgery. The current evidence does not support obligatory embolisation in every case of endoscopic angiofibroma resection.

摘要

目的

确定栓塞术对血管纤维瘤内镜切除术的影响。

研究对象与方法

进行了一项部分盲法试验。2007年1月至2008年8月期间,在两家三级转诊中心,23例血管纤维瘤患者(9例接受栓塞术,14例未接受栓塞术)接受了内镜切除术。收集了人口统计学数据,通过计算机断层扫描评估术前肿瘤范围,并根据计算机断层扫描表现(拉德科夫斯基量表)对肿瘤进行分期。此外,我们评估了手术时间、出血量、手术期间的血压、住院时间、手术和栓塞术的并发症、治疗费用、术后复发次数,以及栓塞组的血管造影特征。

结果

两组的一般特征无显著差异。在研究期结束时,我们发现两组在出血、复发次数或并发症方面无显著差异。唯一显著的差异是治疗费用,栓塞组的费用显著更高。

结论

内镜切除术是血管纤维瘤手术的一种可行且安全的方法。目前的证据不支持在每例内镜下血管纤维瘤切除术中都必须进行栓塞术。

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