Mohammadi Ardehali Mojtaba, Samimi Seyyed Hadi, Bakhshaee Mehdi
Otorhinolaryngology Research Center, Amir Alam Educational Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sinus and Surgical Endoscopic Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Iran J Otorhinolaryngol. 2014 Jan;26(74):25-30.
In recent years, the surgical management of angiofibroma has been greatly influenced by the use of endoscopic techniques. However, large tumors that extend into difficult anatomic sites present major challenges for management by either endoscopy or an open-surgery approach which needs new technique for the complete en block resection.
In a prospective observational study we developed an endoscopic transnasal technique for the resection of angiofibroma via pushing and pulling the mass with 1/100000 soaked adrenalin tampons. Thirty two patients were treated using this endoscopic technique over 7 years. The mean follow-up period was 36 months. The main outcomes measured were tumor staging, average blood loss, complications, length of hospitalization, and residual and/or recurrence rate of the tumor.
According to the Radkowski staging, 23,5, and 4 patients were at stage IIC, IIIA, and IIIB, respectively. Twenty five patients were operated on exclusively via transnasal endoscopy while 7 patients were managed using endoscopy-assisted open-surgery techniques. Mean blood loss in patients was 1261± 893 cc. The recurrence rate was 21.88% (7 cases) at two years following surgery. Mean hospitalization time was 3.56 ± 0.6 days.
Using this effective technique, endoscopic removal of more highly advanced angiofibroma is possible. Better visualization, less intraoperative blood loss, lower rates of complication and recurrence, and shorter hospitalization time are some of the advantages.
近年来,血管纤维瘤的外科治疗受到内镜技术应用的极大影响。然而,延伸至解剖结构复杂部位的大型肿瘤,无论是采用内镜手术还是开放手术进行处理,都面临重大挑战,需要新的技术来实现完整的整块切除。
在一项前瞻性观察研究中,我们开发了一种经鼻内镜技术,通过用浸泡在1/100000肾上腺素棉塞推压和牵拉肿块来切除血管纤维瘤。7年间,32例患者采用了这种内镜技术进行治疗。平均随访期为36个月。主要测量的结果包括肿瘤分期、平均失血量、并发症、住院时间以及肿瘤的残留和/或复发率。
根据Radkowski分期,分别有23例、5例和4例患者处于IIC期、IIIA期和IIIB期。25例患者仅通过经鼻内镜手术,7例患者采用内镜辅助开放手术技术。患者的平均失血量为1261±893毫升。术后两年的复发率为21.88%(7例)。平均住院时间为3.56±0.6天。
使用这种有效技术,有可能通过内镜切除更晚期的血管纤维瘤。更好的视野、更少的术中失血量、更低的并发症和复发率以及更短的住院时间是其一些优点。