Mambrino L J, Kenna M A, Seashore J
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.
Ann Otol Rhinol Laryngol. 1991 Mar;100(3):198-200. doi: 10.1177/000348949110000306.
Congenital tracheal stenosis is a rare disorder that carries a significant morbidity and mortality. It is an even greater challenge when present in combination with other life-threatening congenital anomalies. We present an infant with multiple congenital anomalies, including trisomy 21, who was diagnosed with congenital tracheal stenosis at 3 months of age. At age 5 months, the infant underwent tracheoplasty with costal cartilage graft and pulmonary artery banding. Bronchoscopy 3 weeks later revealed a patent airway. However, the patient died 2 months postoperatively of cardiac complications. At autopsy, whole organ and histologic specimens revealed excellent incorporation of the graft with no evidence of re-stenosis. Our documentation of graft incorporation in this patient is evidence that long segments of stenotic trachea can be successfully treated by tracheoplasty utilizing rib cartilage grafts.
先天性气管狭窄是一种罕见疾病，具有较高的发病率和死亡率。当它与其他危及生命的先天性畸形同时出现时，更是一个巨大的挑战。我们报告一例患有多种先天性畸形（包括21三体综合征）的婴儿，该婴儿在3个月大时被诊断为先天性气管狭窄。5个月大时，该婴儿接受了肋软骨移植气管成形术和肺动脉束带术。3周后的支气管镜检查显示气道通畅。然而，患者术后2个月死于心脏并发症。尸检时，全器官和组织学标本显示移植组织融合良好，无再狭窄迹象。我们对该患者移植组织融合情况的记录证明，利用肋软骨移植进行气管成形术可以成功治疗长段狭窄气管。
