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[经膀胱后间隙闭孔肌复位吊带(Advance)治疗前列腺切除术后尿失禁:累积经验中的教训]

[The treatment of postprostatectomy incontinence with the retroluminal transobturator repositioning sling (Advance): lessons learnt from accumulative experience].

作者信息

Rehder Peter, Freiin von Gleissenthall Gabriele, Pichler Renate, Glodny Berhard

机构信息

Department of Neurology, Neurourology Unit, Innsbruck Medical University, AT 6020 Innsbruck, Austria.

出版信息

Arch Esp Urol. 2009 Dec;62(10):860-70. doi: 10.4321/s0004-06142009001000011.

Abstract

OBJECTIVES

To summarize the lessons learnt after having performed more than 250 AdVance sling procedures. Postprostatectomy incontinence is a depressing reality that is often underestimated by the prostate surgeon. The practiced gold standard for treating severe stress urinary incontinence has been the artificial urinary sphincter. No such consensus exists for mild to moderate incontinence. This paper is about an incontinence operation with the goal to support postprostatectomy sphincter laxity.

METHODS

The hypothesis of postprostatectomy sphincter laxity is new, as well as restoring continence by proximal relocation of the proximal corpus spongiosum. Abstracts dealing with these issues are summarized. Selected points of technique are highlighted, including modifications that have been made along the way. Lastly the first and last 20 patients treated in this series of 250 patients are compared in terms of operative indication, surgical technique and treatment outcome. Some definitions are added for clarity.

RESULTS

It could be demonstrated that the final position of the AdVance sling is retroluminal, i.e. 5-10mm dorsal/behind the lumen of the membranous urethra (=sphincteric urethra). Comparing the first 20 to the last 20, there were no treatment failures in the latter. A two year follow-up showed a continence rate of 65% in the first group, compared to a 85% continence rate in the second group taking into account the short median follow- up of 4.1.months in the latter. Tunneling the sling subcutaneously decreased postoperative loosening significantly.

CONCLUSION

The AdVance sling is a safe method of treating mild to moderate postprostatectomy incontinence, with no erosions in this series of patients. The hypothesis of sphincter laxity seems to play a definitive role in the pathophysiology of male incontinence. Correction of this urethral support descent or "prolapse" seems to be highly effective. Further studies are needed to accurately define the exaxt mechanism of action of the AdVance sling.

摘要

目的

总结在实施超过250例AdVance吊带手术之后所学到的经验教训。前列腺切除术后尿失禁是一个令人沮丧的现实,常常被前列腺外科医生所低估。治疗重度压力性尿失禁的现行金标准是人工尿道括约肌。对于轻至中度尿失禁,尚无此类共识。本文介绍一种旨在改善前列腺切除术后括约肌松弛的尿失禁手术。

方法

前列腺切除术后括约肌松弛的假说以及通过近侧海绵体近端移位恢复控尿功能的假说是全新的。对涉及这些问题的摘要进行了总结。突出了选定的技术要点,包括在实施过程中所做的改进。最后,对这250例患者系列中的前20例和后20例患者在手术指征、手术技术和治疗结果方面进行了比较。为清晰起见增加了一些定义。

结果

可以证明,AdVance吊带的最终位置是位于管腔后方,即距膜性尿道(=括约肌尿道)管腔背侧5-10毫米处。比较前20例和后20例患者,后者没有治疗失败的情况。两年随访显示,第一组的控尿率为65%,而第二组为85%,考虑到第二组的中位随访时间较短,仅为4.1个月。将吊带经皮下隧道放置可显著减少术后松弛。

结论

AdVance吊带是治疗轻至中度前列腺切除术后尿失禁的一种安全方法,在本系列患者中未出现侵蚀现象。括约肌松弛假说似乎在男性尿失禁的病理生理学中起决定性作用。纠正这种尿道支撑下降或“脱垂”似乎非常有效。需要进一步研究以准确界定AdVance吊带的确切作用机制。

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