Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Konya, Turkey.
Gynecol Obstet Invest. 2010;69(4):245-250. doi: 10.1159/000274488. Epub 2010 Jan 12.
In this study, modified biophysical profile (MBP) and uterine and umbilical artery Doppler ultrasonographic (USG) analysis were compared in predicting the perinatal outcome of pregnancies at > or =36 weeks.
Three hundred and fifteen pregnant women were included in this study. Following routine examination, amniotic fluid index, uterine and umbilical artery Doppler indices were evaluated. Nonstress test (NST) was done and MBP was generated. Non-reassuring fetal status (NRFS), perinatal mortality, 5-min APGAR score and umbilical artery pH results were used in evaluating the perinatal outcome.
In groups with abnormal MBP and Doppler analysis the results of all parameters were bad. The statistical difference between the groups of normal and abnormal MBP and Doppler analysis was significant. In predicting the NRFS, MBP sensitivity was 60%, umbilical artery Doppler was 50% and uterine artery Doppler was 30%. In case of combination of findings of MBP and umbilical artery Doppler, the sensitivity rose to 70%.
MBP was proved to be more significant than Doppler analysis in prediction of NRFS and perinatal results, but the sensitivity was increased when both were combined, so combination of MBP and Doppler analysis instead of MBP alone is more significant in antenatal assessment.
本研究旨在比较改良生物物理评分(MBP)和子宫及脐动脉多普勒超声(USG)分析在预测>或=36 周妊娠围产结局中的作用。
本研究纳入了 315 例孕妇。在常规检查后,评估羊水指数、子宫及脐动脉多普勒指数。进行无应激试验(NST)并生成 MBP。使用非胎儿窘迫状态(NRFS)、围产儿死亡率、5 分钟 APGAR 评分和脐动脉 pH 值结果评估围产结局。
在 MBP 和多普勒分析异常的组中,所有参数的结果均较差。MBP 和多普勒分析正常和异常组之间的统计差异具有显著性。在预测 NRFS 时,MBP 的灵敏度为 60%,脐动脉多普勒为 50%,子宫动脉多普勒为 30%。当结合 MBP 和脐动脉多普勒检查结果时,灵敏度升高至 70%。
MBP 预测 NRFS 和围产结局的意义优于多普勒分析,但两者结合时灵敏度增加,因此在产前评估中,MBP 和多普勒分析的联合应用比单独使用 MBP 更有意义。