氨磺必利可改善氯氮平所致的使人衰弱的流涎。

Amisulpride improved debilitating clozapine-induced sialorrhea.

机构信息

Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India.

出版信息

Am J Ther. 2011 May;18(3):e84-5. doi: 10.1097/MJT.0b013e3181c84bbd.

PMID:20068443

Abstract

Clozapine induced sialorrhea is a common and troublesome adverse effect leading to poor treatment compliance. Although there are various treatment options, none has been demonstrated to be superior. In our case study, amisulpride 150 mg/d significantly reduced troublesome daytime sialorrhea along with minimal improvement in nocturnal sialorrhea.

摘要

氯氮平引起的流涎是一种常见且麻烦的不良反应，导致治疗依从性差。尽管有各种治疗选择，但没有一种被证明是优越的。在我们的病例研究中，阿米舒必利 150mg/d 显著减少了白天流涎的麻烦，同时夜间流涎也有最小程度的改善。