Praharaj Samir Kumar, Sarkhel Sujit, Khanande Roshan Vitthalrao, Sinha Vinod Kumar
Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India.
Psychopharmacol Bull. 2010;43(4):73-5.
Clozapine-induced sialorrhea (CIS) is a frequently occurring debilitating adverse effect. Although various treatment options exist, none has been proved to be distinctly superior to others. We report a case of CIS that responded to low dose of trihexyphenidyl (2 mg/day).
氯氮平引起的流涎（CIS）是一种常见的使人衰弱的不良反应。尽管有多种治疗选择，但尚无一种被证明明显优于其他方法。我们报告一例对低剂量苯海索（2毫克/天）有反应的CIS病例。
