Wu Meng-Chieh, Cheng Chen-Chuan, Huang Tsuei-Yuan
Department of Cardiology, Chi-Mei Medical Center, Yong-Kang City, Tainan County 710, Taiwan.
Tex Heart Inst J. 2009;36(6):618-20.
Drug-eluting stents were developed and approved for the reduction of in-stent restenosis. However, restenosis still occurs, and stent fracture is suggested as a cause of restenosis after implantation. Although sirolimus-eluting stents are considered to carry a high risk of fracture, the risk is also present with other drug-eluting stents. Herein, we report the case of a 78-year-old woman who received a zotarolimus-eluting stent for a bifurcation lesion of the left anterior descending coronary artery. Ten months later, she underwent coronary angiography due to angina. The angiogram revealed in-stent restenosis, with a grade IV stent fracture. After percutaneous coronary angioplasty, the patient's clinical symptoms improved.
药物洗脱支架被研发并获批用于减少支架内再狭窄。然而，再狭窄仍会发生，且支架断裂被认为是植入后再狭窄的一个原因。尽管西罗莫司洗脱支架被认为具有较高的断裂风险，但其他药物洗脱支架也存在这种风险。在此，我们报告一例78岁女性患者，其因左前降支冠状动脉分叉病变接受了佐他莫司洗脱支架植入。十个月后，她因心绞痛接受冠状动脉造影。血管造影显示支架内再狭窄，并伴有IV级支架断裂。经皮冠状动脉腔内血管成形术后，患者的临床症状有所改善。
