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自膨式金属支架姑息治疗恶性吞咽困难:124 例埃及患者的结果。

Self-expanding metal stents in palliation of malignant dysphagia: outcome of 124 Egyptian patients.

机构信息

Department of Otorhinolaryngology, Mansoura University Hospital, Mansoura University, Mansoura, Egypt.

出版信息

Eur Arch Otorhinolaryngol. 2010 Jul;267(7):1123-7. doi: 10.1007/s00405-009-1198-y. Epub 2010 Jan 13.

Abstract

Most cases of esophageal carcinoma are inoperable at presentation. Currently, the best method for palliation of malignant dysphagia, with or without esophago-respiratory fistula, is an insertion of esophageal self-expanding metal stents (SEMS) across the malignant esophageal stricture. Herein we present our experience in the use of SEMS in palliation of patients with malignant dysphagia and/or ERF. The study included 124 patients (79 males and 45 females) with advanced esophageal malignancy. The mean age was 54 (43-87) years. Nine patients had malignant ERF. All patients were subjected to SEMS insertion under both endoscopic and fluoroscopic guidance. SEMS insertion was successful in all patients. Nine patients had two stents. Median dysphagia score improved from 3.5 to 1.2. ERF was sealed in eight out of the nine patients. Complications related to stent implementation were reported in 41 patients. In conclusion, insertion of the SEMS is a reliable, effective, simple and safe method for palliation of malignant dysphagia with or without ERF.

摘要

大多数食管癌病例在就诊时无法手术。目前,对于恶性吞咽困难(伴或不伴食管-呼吸道瘘)的缓解,最好的方法是在恶性食管狭窄处插入食管自膨式金属支架(SEMS)。在此,我们介绍了我们在使用 SEMS 缓解恶性吞咽困难和/或 ERF 患者方面的经验。该研究包括 124 名患有晚期食管恶性肿瘤的患者(79 名男性和 45 名女性)。平均年龄为 54 岁(43-87 岁)。9 名患者有恶性 ERF。所有患者均在内镜和透视引导下进行 SEMS 插入。所有患者的 SEMS 插入均成功。9 名患者有两个支架。中位吞咽困难评分从 3.5 分提高到 1.2 分。在 9 名患者中,有 8 名患者的 ERF 得到了封闭。41 名患者报告了与支架实施相关的并发症。总之,SEMS 的插入是一种可靠、有效、简单和安全的方法,可缓解恶性吞咽困难伴或不伴 ERF。

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