School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.
Ir J Med Sci. 2010 Mar;179(1):119-21. doi: 10.1007/s11845-009-0460-z.
Douglas Argyll Robertson's (1837-1909) experimental work with physostigmine in 1863 sharpened his knowledge of the innervation of the internal muscles of the eye. So he was ideally prepared in 1869 to analyse the conundrum when he saw patients with spinal cord disease who had lost the response to light even though accommodation to near objects was normal. By translating his knowledge of basic science to a clinical problem he drew attention to this phenomenon, known subsequently as the Argyll Robertson pupil that came to be considered pathognomonic of tabes dorsalis, general paresis and neurovascular syphilis.
道格拉斯·阿盖尔·罗伯逊（Douglas Argyll Robertson）在 1863 年对毒扁豆碱的实验研究加深了他对眼睛内部肌肉神经支配的认识。因此，1869 年当他看到患有脊髓疾病的患者即使对近物的调节正常，对光的反应也消失时，他能够理想地分析这个难题。通过将他的基础科学知识转化为临床问题，他引起了对这种现象的关注，后来被称为阿盖尔-罗伯逊瞳孔，被认为是脊髓痨、麻痹性痴呆和神经血管性梅毒的特征性表现。
