Department of Neurosurgery, Division of Clinical Neuroscience, Rikshospitalet University Hospital, Oslo, Norway.
Acta Neurol Scand. 2010 Oct;122(4):262-9. doi: 10.1111/j.1600-0404.2009.01304.x. Epub 2010 Jan 11.
To characterize the association between arterial blood pressure (ABP) and intracranial pressure (ICP) in idiopathic normal pressure hydrocephalus (iNPH) patients, and its impact on outcome of shunt surgery.
We analyzed all 35 iNPH patients whose ABP and ICP were recorded simultaneously during 6 years (2002-2007). The static and pulsatile pressures were averaged over consecutive 6-s intervals; the moving correlations between ICP and ABP (static and pulsatile) were determined during consecutive 4-min periods to explore time-related variations.
Neither static nor pulsatile ABP were altered in iNPH shunt responders. Elevated pulsatile ICP, but normal static ICP, was seen in responders. The time-varying correlations of static and of pulsatile pressures were generally low, and did not differ between shunt responders/non-responders.
In iNPH shunt responders, static or pulsatile ABP were not altered and only pulsatile ICP was elevated.
描述特发性正常压力脑积水（iNPH）患者的动脉血压（ABP）和颅内压（ICP）之间的关系及其对分流手术结果的影响。
我们分析了 2002 年至 2007 年间连续 6 年期间同时记录 ABP 和 ICP 的 35 例 iNPH 患者。连续 6 秒间隔内平均静态和脉动压力；在连续 4 分钟期间确定 ICP 和 ABP（静态和脉动）之间的移动相关性，以探索时间相关变化。
分流反应者的静态或脉动 ABP 均未改变。在反应者中，可见搏动性 ICP 升高，而静态 ICP 正常。静态和脉动压力的时变相关性通常较低，并且在分流反应者/非反应者之间没有差异。
在 iNPH 分流反应者中，静态或脉动 ABP 未改变，只有脉动 ICP 升高。
Zotero 插件