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尿道狭窄的尿道成形术:家庭算法的质量评估。

Urethroplasty for urethral strictures: quality assessment of an in-home algorithm.

机构信息

Department of Urology, Ghent University Hospital, Ghent, Belgium.

出版信息

Int J Urol. 2010 Feb;17(2):167-74. doi: 10.1111/j.1442-2042.2009.02435.x. Epub 2010 Jan 12.

Abstract

OBJECTIVES

To evaluate the outcome of different techniques of urethroplasty and to assess the quality of an in-home algorithm.

METHODS

Two hundred fifty-two male patients underwent urethroplasty. Mean patient's age was 48 years (range 1-85 years). Data were analyzed for the failure rate of the different techniques of urethroplasty. An additional analysis was done based on an in-home algorithm.

RESULTS

Median follow up was 37 months (range: 6-92 months). Global failure rate was 14.9%, with an individual failure rate of 11.7%, 16.0%, 20.7% and 20.8% for anastomotic repair, free graft urethroplasty, pedicled flap urethroplasty and combined urethroplasty, respectively. In free graft urethroplasty, results were significantly worse when extrapreputial skin was used. Anastomotic repair was the principle technique for short strictures (83.3%), at the bulbar and posterior urethra (respectively 50.8 and 100%). Free graft urethroplasty was mainly used for 3-10 cm strictures (58.6%). Anastomotic repair and free graft urethroplasty were more used in case of no previous interventions or after urethrotomy/dilation. Pedicled flap urethroplasty was the main technique at the penile urethra (40.7%). Combined urethroplasty was necessary in 41 and 47.1% in the treatment of, respectively, >10 cm or panurethral/multifocal anterior urethral strictures and was the most important technique in these circumstances. Two-stage urethroplasty or perineostomy were only used in 2% as first-line treatment but were already used in 14.9% after failed urethroplasty.

CONCLUSION

Urethroplasty has good results at intermediate follow up. Different types of techniques must be used for different types of strictures.

摘要

目的

评估不同尿道成形术技术的结果,并评估家庭算法的质量。

方法

252 名男性患者接受了尿道成形术。患者平均年龄为 48 岁(范围 1-85 岁)。分析了不同尿道成形术技术的失败率。还根据家庭算法进行了额外分析。

结果

中位随访时间为 37 个月(范围:6-92 个月)。总的失败率为 14.9%,吻合修复、游离移植物尿道成形术、带蒂皮瓣尿道成形术和联合尿道成形术的个体失败率分别为 11.7%、16.0%、20.7%和 20.8%。在游离移植物尿道成形术中,使用额外的包皮皮肤时结果明显更差。吻合修复是短狭窄的主要技术(83.3%),在球部和后尿道(分别为 50.8%和 100%)。游离移植物尿道成形术主要用于 3-10 厘米的狭窄(58.6%)。吻合修复和游离移植物尿道成形术更多地用于没有先前干预或尿道切开术/扩张后的情况。带蒂皮瓣尿道成形术是阴茎尿道的主要技术(40.7%)。联合尿道成形术分别在 10 厘米以上或全尿道/多灶性前尿道狭窄的治疗中是必要的,在这些情况下是最重要的技术。两阶段尿道成形术或会阴切开术仅作为一线治疗在 2%的情况下使用,但在尿道成形术失败后已在 14.9%的情况下使用。

结论

尿道成形术在中期随访中具有良好的结果。必须针对不同类型的狭窄使用不同类型的技术。

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