Department of Dermatology, Gaziosmanpasa University School of Medicine, Tokat, Turkey.
Photodermatol Photoimmunol Photomed. 2010 Feb;26(1):48-50. doi: 10.1111/j.1600-0781.2009.00482.x.
Clear cell Bowen's disease (BD) is a rare histopathological subtype of BD, characterized by epidermal atypical keratinocytes with clear-cell changes exceeding 80% of the tumor population. Warty and clear cell Bowen's disease (WCCBD) is a recently described variant of clear cell BD, with verrucous and hyperkeratotic surface changes in addition to pathological features consisting of an extremely acanthotic epidermis, hyperkeratosis and clear-cell changes. Herein we present a 72-year-old man with a 1-year history of tumoral lesion located on the left cheek with a diagnosis of WCCBD, in whom we achieved excellent result with photodynamic treatment. To the best of our knowledge, this is the second reported case of this entity.
透明细胞鲍恩病(BD)是一种罕见的 BD 组织病理学亚型,其特征是表皮非典型角质形成细胞的透明细胞改变超过肿瘤人群的 80%。疣状和透明细胞鲍恩病(WCCBD)是透明细胞 BD 的一种最近描述的变体,除了病理学特征包括极度棘皮病、角化过度和透明细胞改变外,还有疣状和角化过度的表面变化。在此,我们报告了一名 72 岁男性,其左侧脸颊有 1 年的肿瘤病变史,诊断为 WCCBD,我们通过光动力治疗取得了极佳的效果。据我们所知,这是该实体的第二例报道。