IC Design and Fabrication Centre, Department of Electronics and Telecommunication Engineering, Jadavpur University, India.
Comput Biol Med. 2010 Feb;40(2):190-200. doi: 10.1016/j.compbiomed.2009.11.015. Epub 2010 Jan 13.
The paper describes the design and training of a fuzzy neural network used for early diagnosis of a patient through an FPGA based implementation of a smart instrument. The system employs a fuzzy interface cascaded with a feed-forward neural network. In order to obtain an optimum decision regarding the future pathophysiological state of a patient, the optimal weights of the synapses between the neurons have been determined by using inverse delayed function model of neurons. The neurons that are considered in the proposed network are devoid of self connections instead of commonly used self connected neurons. The current work also find out the optimal number of neurons in the hidden layer for accurate diagnosis as against the available number of CLB in the FPGA. The system has been trained and tested with renal data of patients taken at 10 days interval of time. Applying the methodology, the chance of attainment of critical renal condition of a patient has been predicted with an accuracy of 95.2%, 30 days ahead of actually attaining the critical condition. The system has also been tested for pathophysiological state prediction of patients at multiple time steps ahead and the prediction at the next instant of time stands out to be the most accurate.
本文描述了一种模糊神经网络的设计和训练,该网络通过基于 FPGA 的智能仪器实现,用于对患者进行早期诊断。该系统采用模糊接口与前馈神经网络级联。为了对患者未来的病理生理状态做出最佳决策,利用神经元的逆延迟函数模型确定了神经元之间突触的最佳权重。与常用的自连接神经元不同,所提出的网络中考虑的神经元没有自连接。当前的工作还发现,针对 FPGA 中可用的 CLB 数量,在隐藏层中获得准确诊断所需的最佳神经元数量。该系统已经使用患者的肾脏数据进行了训练和测试,这些数据是在 10 天的时间间隔内采集的。应用该方法,可以在患者实际达到危急状态前 30 天,以 95.2%的准确率预测患者达到危急肾脏状况的可能性。该系统还针对患者在多个时间步长的病理生理状态进行了预测,而下一时刻的预测结果最为准确。