Bigeleisen P E, Kang Y
Department of Anesthesiology, University of Pittsburgh School of Medicine, Presbyterian-University Hospital, Pennsylvania 15213.
Reg Anesth. 1991 Jan-Feb;16(1):59-61.
Thrombelastography (TEG), a less commonly available technique used to assess hemostatic function, has recently gained popularity. Analysis of TEG yields qualitative information about platelet function, thromboplastin generation and their interaction with the intrinsic cascade to form a stable clot. Additional information is obtained about fibrinogen and Factor XIII levels as well as the fibrinolytic system. TEG has been shown to be more sensitive and accurate than traditional coagulation tests at both predicting and treating coagulopathies. We report here three cases in which TEG was used to assess hemostatic function in patients at risk for bleeding prior to the induction of regional anesthesia. In all three cases, traditional tests were inadequate to predict the safe practice of regional anesthesia. TEG provided this information and regional anesthesia was successfully employed.
血栓弹力图(TEG)是一种用于评估止血功能的不太常用的技术,最近受到了广泛关注。对TEG的分析可得出有关血小板功能、凝血活酶生成及其与内源性凝血途径相互作用以形成稳定凝块的定性信息。还可获得有关纤维蛋白原和因子 XIII 水平以及纤维蛋白溶解系统的额外信息。在预测和治疗凝血病方面,TEG 已被证明比传统凝血试验更敏感、更准确。我们在此报告三例使用TEG评估区域麻醉诱导前有出血风险患者止血功能的病例。在所有三例中,传统检查不足以预测区域麻醉的安全实施。TEG提供了这些信息,区域麻醉得以成功实施。