Department of Plastic Surgery and Hand Surgery, Erasmus University Medical Center and Sint Franciscus Hospital, Office HS-511, Rotterdam, The Netherlands.
Burns. 2010 Aug;36(5):593-8. doi: 10.1016/j.burns.2009.10.007. Epub 2010 Jan 13.
In extensive burns peripheral nerves can be involved. The injury to the nerve can be direct by thermal or electrical burns, but nerves can also be indirectly affected by the systemic reaction that follows the burn. Mediators will be released causing a neuropathy to nerves remote from the involved area. Involved mediators and possible therapeutic options will be discussed. In burned patients nerves can be reconstructed using autologous nerve grafts or nerve conduits. A key factor is an adequate wound debridement and a well-vascularized bed to optimize the outgrowth of the axons. Early free tissue transfers have shown promising results.
在大面积烧伤中，周围神经可能会受到影响。神经损伤可能是由热或电烧伤直接引起的，但神经也可能会受到烧伤后全身性反应的间接影响。介质的释放会导致远离受累区域的神经发生神经病变。本文将讨论涉及的介质和可能的治疗选择。在烧伤患者中，可以使用自体神经移植物或神经导管来重建神经。一个关键因素是进行充分的清创和使床有良好的血供，以优化轴突的生长。早期游离组织转移已显示出良好的效果。
