Breast Unit, Luton & Dunstable Hospital NHS Foundation Trust, Lewsey Road, Luton LU4 0DZ, Bedfordshire, United Kingdom.
Breast. 2010 Apr;19(2):150-1. doi: 10.1016/j.breast.2009.12.007. Epub 2010 Jan 13.
Triple assessment of breast lesions usually involves the use of core biopsy (CB) or fine needle aspiration cytology (FNAC). Punch Biopsy (PB) is a technique widely used by dermatologists and can be used in superficial breast lesions with dermal involvement. We studied the utilization of PB in a rapid diagnosis breast clinic.
We reviewed patients who underwent a PB over a seven and a half-year period from December 2001 to May 2009. The indications for biopsy and the contribution of PB to final diagnosis were studied.
The commonest indications were breast lump with skin involvement or ulceration (n = 27), suspected Paget's disease (n = 25), discolouration of breast skin (n = 23), and nodules in the breast skin or surgical scar (n = 18). Final diagnosis was benign in 80 patients and malignant in 20. In 74 patients with benign and 7 patients with malignant diagnoses, PB was the only source of histological diagnosis.
PB is a valuable adjunct to conventional methods of tissue diagnosis such as CB and FNAC in both benign and malignant breast lesions.
乳腺病变的三联评估通常需要进行核心活检(CB)或细针穿刺细胞学检查(FNAC)。打孔活检(PB)是皮肤科医生广泛使用的一种技术,可用于涉及皮肤的浅表乳腺病变。我们研究了 PB 在快速诊断乳腺门诊中的应用。
我们回顾了 2001 年 12 月至 2009 年 5 月期间进行 PB 的患者。研究了活检的适应证以及 PB 对最终诊断的贡献。
最常见的适应证是伴有皮肤受累或溃疡的乳腺肿块(n=27)、疑似乳腺佩吉特病(n=25)、乳腺皮肤变色(n=23)和乳腺皮肤结节或手术瘢痕(n=18)。80 例患者的最终诊断为良性,20 例为恶性。在 74 例良性和 7 例恶性诊断的患者中,PB 是唯一的组织学诊断来源。
PB 是 CB 和 FNAC 等传统组织诊断方法的有益补充,可用于良性和恶性乳腺病变。