Ravichandran D, Naz S
Breast Unit, Luton and Dunstable Hospital, Lewsey Road, Luton LU4 0DZ, Bedfordshire, United Kingdom.
Eur J Pediatr Surg. 2006 Oct;16(5):303-6. doi: 10.1055/s-2006-924616.
Children and adolescents referred to a rapid diagnosis breast clinic were analysed to study the conditions these patients were referred with, their management, and the final outcome.
All new patients aged 18 or under seen in a breast clinic over a 39-month period to June 2004 were identified and their case notes were reviewed.
Among 6930 new referrals, 88 (1.3 %) were aged 18 or under and 86 patients were included in the study (median age 16 yrs, range 8 - 18 yrs). Five patients were aged less than 12 and were referred with physiological breast buds. In girls aged 13 - 18 years, most were referred for an apparent palpable abnormality. Thirty percent had a family history of breast carcinoma and 35 % were on the oral contraceptive pill. Thirty-three patients (38 %) had a clinical examination only. Others, in addition to the clinical examination, had an ultrasound (US) (n = 24, 28 %), fine needle aspiration cytology (FNAC)/core biopsy (CB) (n = 5, 6 %) or both US and FNAC/CB (triple assessment) (n = 24, 28 %). No malignant disease was found. No diagnostic biopsies were performed. Only 5 patients had surgery, four for fibroadenoma and one for sebaceous cyst.
Patients aged 18 years or under do not constitute a major workload problem for rapid diagnosis breast clinics. Malignant disease remains rare. A significant proportion of patients require only clinical examination and reassurance. The diagnosis can usually be made without open biopsies and less invasively using FNAC or CB.
对转诊至快速诊断乳腺门诊的儿童及青少年进行分析,以研究这些患者的转诊病情、治疗及最终结果。
确定2004年6月前39个月内在乳腺门诊就诊的所有18岁及以下新患者,并查阅其病历。
在6930例新转诊患者中,88例(1.3%)年龄在18岁及以下,86例患者纳入研究(中位年龄16岁,范围8 - 18岁)。5例年龄小于12岁,因生理性乳腺芽转诊。13 - 18岁女孩中,大多数因明显可触及异常转诊。30%有乳腺癌家族史,35%正在服用口服避孕药。33例患者(38%)仅接受了临床检查。其他患者除临床检查外,还接受了超声检查(n = 24,28%)、细针穿刺细胞学检查(FNAC)/粗针活检(CB)(n = 5,6%)或超声检查与FNAC/CB两者(三联评估)(n = 24,28%)。未发现恶性疾病。未进行诊断性活检。仅5例患者接受了手术,4例因纤维腺瘤,1例因皮脂腺囊肿。
18岁及以下患者对快速诊断乳腺门诊而言不构成主要工作量问题。恶性疾病仍然罕见。相当一部分患者仅需临床检查及安心处理。通常无需开放活检,使用FNAC或CB进行微创检查即可做出诊断。