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一项针对转诊至快速诊断乳腺门诊的儿童和青少年的研究。

A study of children and adolescents referred to a rapid diagnosis breast clinic.

作者信息

Ravichandran D, Naz S

机构信息

Breast Unit, Luton and Dunstable Hospital, Lewsey Road, Luton LU4 0DZ, Bedfordshire, United Kingdom.

出版信息

Eur J Pediatr Surg. 2006 Oct;16(5):303-6. doi: 10.1055/s-2006-924616.

Abstract

AIM

Children and adolescents referred to a rapid diagnosis breast clinic were analysed to study the conditions these patients were referred with, their management, and the final outcome.

METHODS

All new patients aged 18 or under seen in a breast clinic over a 39-month period to June 2004 were identified and their case notes were reviewed.

RESULTS

Among 6930 new referrals, 88 (1.3 %) were aged 18 or under and 86 patients were included in the study (median age 16 yrs, range 8 - 18 yrs). Five patients were aged less than 12 and were referred with physiological breast buds. In girls aged 13 - 18 years, most were referred for an apparent palpable abnormality. Thirty percent had a family history of breast carcinoma and 35 % were on the oral contraceptive pill. Thirty-three patients (38 %) had a clinical examination only. Others, in addition to the clinical examination, had an ultrasound (US) (n = 24, 28 %), fine needle aspiration cytology (FNAC)/core biopsy (CB) (n = 5, 6 %) or both US and FNAC/CB (triple assessment) (n = 24, 28 %). No malignant disease was found. No diagnostic biopsies were performed. Only 5 patients had surgery, four for fibroadenoma and one for sebaceous cyst.

CONCLUSIONS

Patients aged 18 years or under do not constitute a major workload problem for rapid diagnosis breast clinics. Malignant disease remains rare. A significant proportion of patients require only clinical examination and reassurance. The diagnosis can usually be made without open biopsies and less invasively using FNAC or CB.

摘要

目的

对转诊至快速诊断乳腺门诊的儿童及青少年进行分析,以研究这些患者的转诊病情、治疗及最终结果。

方法

确定2004年6月前39个月内在乳腺门诊就诊的所有18岁及以下新患者,并查阅其病历。

结果

在6930例新转诊患者中,88例(1.3%)年龄在18岁及以下,86例患者纳入研究(中位年龄16岁,范围8 - 18岁)。5例年龄小于12岁,因生理性乳腺芽转诊。13 - 18岁女孩中,大多数因明显可触及异常转诊。30%有乳腺癌家族史,35%正在服用口服避孕药。33例患者(38%)仅接受了临床检查。其他患者除临床检查外,还接受了超声检查(n = 24,28%)、细针穿刺细胞学检查(FNAC)/粗针活检(CB)(n = 5,6%)或超声检查与FNAC/CB两者(三联评估)(n = 24,28%)。未发现恶性疾病。未进行诊断性活检。仅5例患者接受了手术,4例因纤维腺瘤,1例因皮脂腺囊肿。

结论

18岁及以下患者对快速诊断乳腺门诊而言不构成主要工作量问题。恶性疾病仍然罕见。相当一部分患者仅需临床检查及安心处理。通常无需开放活检,使用FNAC或CB进行微创检查即可做出诊断。

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