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1990 年至 2005 年期间,西澳大利亚心力衰竭的发病率、病死率和住院率。

Heart failure: incidence, case fatality, and hospitalization rates in Western Australia between 1990 and 2005.

机构信息

School of Population Health, University of Western Australia, Perth, Western Australia.

出版信息

Circ Heart Fail. 2010 Mar;3(2):236-43. doi: 10.1161/CIRCHEARTFAILURE.109.879239. Epub 2010 Jan 13.

Abstract

BACKGROUND

We examined trends in incidence of first-ever (index) hospitalization for heart failure (HF), hospitalization rates, and 30-day and 1-year all-cause mortality subsequent to index hospitalization for HF.

METHODS AND RESULTS

The Western Australia Hospital Morbidity Database was used to identify a retrospective population-based cohort with an index hospitalization for HF in Western Australia between 1990 and 2005. Risk-adjusted temporal trends in mortality were examined with the use of multivariable logistic regression models. Baseline period for comparison was 1990-1993. The cohort (n=19 342; mean age, 74.2+/-13.2 years; 51.3% men) was followed until death or end of 2006. During the period of 1990-2005, age-standardized rates (per 100,000) of index hospitalization for HF as a principal diagnosis decreased from 191.0 to 103.2 in men, with an annual decrease of 3.5%, and from 130.5 to 75.1 in women, with an annual decrease of 3.1%. Risk-adjusted odds ratio of death at 30 days decreased to 0.73 (95% CI, 0.65 to 0.81) based on nonelective admissions. Risk-adjusted odds ratio of 1-year mortality also decreased during the study period in both genders and across all age groups. The total number of HF hospitalizations increased, with nonelective admissions increasing by 14.9% (P for trend, <0.0001) during this period. However, age-standardized rates of nonelective HF hospitalizations decreased during the same period.

CONCLUSIONS

During the 16-year period studied, the incidence of index hospitalization for HF in Western Australia decreased steadily in both genders. However, hospitalizations for HF as a measure of health service use increased, despite decreasing rates, partly because of an aging population and improved HF survival.

摘要

背景

我们研究了首次(索引)因心力衰竭(HF)住院的发病率、住院率,以及索引 HF 住院后 30 天和 1 年全因死亡率的趋势。

方法和结果

我们使用西澳大利亚州医院发病率数据库来确定 1990 年至 2005 年间在西澳大利亚州首次因 HF 住院的回顾性人群队列。使用多变量逻辑回归模型检查死亡率的时间趋势。比较的基线期为 1990-1993 年。该队列(n=19342;平均年龄 74.2+/-13.2 岁;51.3%为男性)随访至死亡或 2006 年底。在 1990-2005 年期间,作为主要诊断的 HF 索引住院率(每 10 万人),男性从 191.0 降至 103.2,每年下降 3.5%,女性从 130.5 降至 75.1,每年下降 3.1%。基于非选择性入院,30 天死亡风险调整后的比值比降低至 0.73(95%CI,0.65-0.81)。在研究期间,两性和所有年龄组的 1 年死亡率风险调整比值比均下降。HF 住院总人数增加,非选择性入院人数增加 14.9%(趋势 P<0.0001)。然而,同期非选择性 HF 住院率下降。

结论

在研究的 16 年期间,西澳大利亚州男女 HF 索引住院的发病率稳步下降。然而,尽管住院率下降,但 HF 住院作为卫生服务利用的衡量标准增加,这部分是由于人口老龄化和 HF 生存率提高。

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