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尼泊尔加德满都医学院胆石症患者中不同类型胆结石的患病率。

Prevalence of different types of gallstone in the patients with cholelithiasis at Kathmandu Medical College, Nepal.

作者信息

Pradhan Sailesh B, Joshi M R, Vaidya A

机构信息

Department of Pathology, Kathmandu Medical College & Teaching Hospital, Sinamangal, Kathmandu, Nepal.

出版信息

Kathmandu Univ Med J (KUMJ). 2009 Jul-Sep;7(27):268-71. doi: 10.3126/kumj.v7i3.2736.

Abstract

BACKGROUND

Gallstone disease known as cholelithiasis is the most common digestive surgical disorder and account for an important part of health care expenditure. Attempt was made to analyse the gallstone for typing depending upon the composition.

AIMS & OBJECTIVES: The main objective of this study was to see the prevalence of different types of gallstone in Nepal and to correlate them with the clinical findings.

MATERIALS & METHODS: Gallstones of 80 different patients who underwent cholecystectomy for cholelithiasis were collected from 20th January 2005 to 16th May 2006 in Department of Pathology, Kathmandu Medical College Teaching Hospital. Detailed history was taken. Stones were analyzed with chemical and enzymatic methods using clinical spectrophotometer.

RESULTS & CONCLUSION: The most commonly involved age group for cholelithiasis (32.5%) is found to be 30-39 years with a female predominance (M: F=1:3.2). Cholelithiasis was found more commonly among non-vegetarian with the vegetarian: non-vegetarian ratio 1:9. Mixed type stone was found to be the most common type of stone comprising 78.75%, followed by cholesterol stone 12.5%, Brown pigment stone 7.5% and Black pigment stone 1.25%.

摘要

背景

胆结石病即胆石症,是最常见的消化系统外科疾病,在医疗保健支出中占重要部分。已尝试根据成分对胆结石进行分型分析。

目的

本研究的主要目的是了解尼泊尔不同类型胆结石的患病率,并将其与临床发现相关联。

材料与方法

2005年1月20日至2006年5月16日期间,从加德满都医学院教学医院病理科收集了80例因胆石症接受胆囊切除术患者的胆结石。记录详细病史。使用临床分光光度计通过化学和酶学方法对结石进行分析。

结果与结论

胆石症最常累及的年龄组(32.5%)为30 - 39岁,女性居多(男∶女 = 1∶3.2)。在非素食者中胆石症更为常见,素食者与非素食者的比例为1∶9。混合型结石是最常见的结石类型,占78.75%,其次是胆固醇结石占12.5%,棕色色素结石占7.5%,黑色色素结石占1.25%。

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