Tabrizi Reza, Arabi Ali Mohammad, Arabion Hamid Reza, Gholami Mehdi
Department of Maxillofacial Surgery, Shiraz University of Medical Sciences, Craniomaxillofacial Research Center, Shiraz, Iran.
J Craniofac Surg. 2010 Jan;21(1):136-41. doi: 10.1097/SCS.0b013e3181c46df2.
Osteopetrosis is a rare bone dysplasia. The disease is characterized by osteoclast dysfunction, producing diffuse symmetrical increase in skeletal bone density and exhibiting various clinical manifestation because of heterogeneous entity. Among them, jaw osteomyelitis, frequently mandibular osteomyelitis, is an important complication encountered in these patients. In this article, 2 patients diagnosed with osteopetrosis with mandibular osteomyelitis would be presented. We used debridement and decortications, removal of hopeless teeth, and topical phenytoin in the management of mandibular osteomyelitis.
骨质石化症是一种罕见的骨发育异常疾病。该疾病的特征是破骨细胞功能障碍，导致全身骨骼密度弥漫性对称性增加，并且由于其异质性而表现出各种临床表现。其中，颌骨骨髓炎，通常是下颌骨骨髓炎，是这些患者中遇到的一种重要并发症。在本文中，将介绍2例被诊断为骨质石化症合并下颌骨骨髓炎的患者。我们采用清创术、骨皮质切除术、拔除无保留价值的牙齿以及局部应用苯妥英钠来治疗下颌骨骨髓炎。
