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人类气管软骨骨钙素化生的研究II. 气管软骨的组织病理学检查

Investigations into human tracheal cartilage osseocalcineus metaplasia II. Histopathological examination of tracheal cartilages.

作者信息

Sośnik Henryk, Sośnik Katarzyna

机构信息

Department of Pathomorphology, "Hist-Med", Regional Specialist Hospital, Wrocław.

出版信息

Pol J Pathol. 2009;60(4):179-85.

PMID:20072952
Abstract

Different opinions in the literature about changes in tracheal cartilages were the basis for investigations concerning the types of morphological changes occurring in ageing tracheal cartilages. 5 micron thick specimens stained with haematoxylin-eosin and in selected cases using von Kossa method of 371 cartilages taken from 95 male (mean age 56.6 +/-13.4 years) and 279 cartilages from 70 female patients (mean age 64.9 +/-16 years) (p < 0.001) were the investigated material. The analysis demonstrated statistically significant cartilage type differences between men and women (p < 0.001). Chondrolysis and asbestoids were observed in 11.9% of male and 2.9% of female patients. Calcium deposits were seen in 13.2% of male and 9.7% of female patients, while cartilage ossification in 20.5% and 3.6%, respectively. The coexistence of calcium deposits and osseous metaplasia was observed in 8.6% of male and 3.9% of female patients.

摘要

文献中关于气管软骨变化的不同观点是对衰老气管软骨发生的形态学变化类型进行研究的基础。对取自95名男性(平均年龄56.6±13.4岁)的371块软骨和70名女性患者(平均年龄64.9±16岁)(p<0.001)的279块软骨制作的5微米厚苏木精-伊红染色标本,以及在选定病例中使用冯·科萨方法制作的标本进行研究。分析表明,男性和女性之间软骨类型存在统计学显著差异(p<0.001)。在11.9%的男性患者和2.9%的女性患者中观察到软骨溶解和石棉样变。在13.2%的男性患者和9.7%的女性患者中发现钙沉积,而软骨骨化分别为20.5%和3.6%。在8.6%的男性患者和3.9%的女性患者中观察到钙沉积和骨化生并存。

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Investigations into human tracheal cartilage osseocalcineus metaplasia II. Histopathological examination of tracheal cartilages.人类气管软骨骨钙素化生的研究II. 气管软骨的组织病理学检查
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