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[支气管曲霉病]

[Bronchial aspergillosis].

作者信息

Dobbertin I, Friedel G, Jaki R, Michl M, Kimmich M, Hofmann A, Eulenbruch H-P, Weber J, Spengler W, Ott G, Kohlhäufl M

机构信息

Klinik Schillerhöhe, Zentrum für Pneumologie und Thoraxchirurgie der Robert-Bosch-Krankenhaus GmbH, Stuttgart.

出版信息

Pneumologie. 2010 Mar;64(3):171-83. doi: 10.1055/s-0029-1215306. Epub 2010 Jan 12.

Abstract

Bronchopulmonary aspergillosis is becoming more frequent, is often hard to diagnose and with today's antimycotics better to treat than before. It is therefore of current interest. This also concerns bronchial aspergillosis which is less common than pulmonary aspergillosis and the topic of this paper. A total of 39 patients with bronchial aspergillosis are presented: 1) 4 cases with endobronchial aspergilla, two which are visual bronchoscopically, 2) one case with chronic necrotising pulmonary aspergillosis (CNPA), where a bronchus has necrotised, 3) an invasive aspergillosis in the region of a bronchial anastomosis, 4) 7 cases with an Aspergillus invasion from endobronchial tumour tissue and 5) 26 cases with allergic bronchopulmonary aspergillosis (ABPA). 37 of the 39 cases are part of a single centre study with a total of 116 bronchopulmonary aspergilloses, which were collected over seven years. The focus of attention in this paper is on the bronchoscopic and radiological results.

摘要

支气管肺曲霉菌病正变得越来越常见,常常难以诊断,而如今使用抗真菌药物治疗比以前效果更好。因此,它是当前研究的热点。这也涉及到比肺曲霉菌病少见的支气管曲霉菌病,本文将探讨这一主题。本文共介绍了39例支气管曲霉菌病患者:1)4例支气管内曲霉菌病,其中2例可通过支气管镜直视观察到;2)1例慢性坏死性肺曲霉菌病(CNPA),伴有支气管坏死;3)1例支气管吻合部位的侵袭性曲霉菌病;4)7例曲霉菌从支气管内肿瘤组织侵袭的病例;5)26例变应性支气管肺曲霉菌病(ABPA)。39例中的37例是一项单中心研究的一部分,该研究共收集了116例支气管肺曲霉菌病病例,历时7年。本文关注的重点是支气管镜检查和放射学检查结果。

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