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18个月女童额骨巨细胞瘤:一例报告

Giant cell tumor of the frontal bone in an 18-month-old girl: a case report.

作者信息

Ulu M O, Biceroglu H, Ozlen F, Oz B, Gazioglu N

机构信息

Sakarya ToyotaSA State Hospital, Department of Neurosurgery, Sakarya, Turkey.

出版信息

Cent Eur Neurosurg. 2010 May;71(2):104-7. doi: 10.1055/s-0029-1243200. Epub 2010 Jan 13.

Abstract

INTRODUCTION

Giant cell tumors (GCT) are benign, but locally aggressive primary bone neoplasms, that frequently occur in the epiphyses of the long bones. Less than 1% of all GCTs primarily involve the skull where they are preferentially seen in the sphenoid and temporal bones. In the pediatric age group they are exceptionally rare.

CASE REPORT

The authors report the management of a GCT involving the frontal bone in an 18-month-old girl. The patient underwent wide surgical excision of the lesion and remains free of clinical and radiological evidence of tumoral recurrence thirty months after treatment.

CONCLUSION

Although rare, GCTs should be taken into consideration as a differential diagnosis of rapidly enlarging cranial mass lesions in pediatric patients. Gross total surgical excision eliminates the potential risks of adjuvant radiotherapy. However, considering the aggressive nature and potential malignancy of these lesions, careful long-term clinical and imaging follow-up is recommended.

摘要

引言

骨巨细胞瘤(GCT)是良性但具有局部侵袭性的原发性骨肿瘤,常发生于长骨的骨骺。在所有骨巨细胞瘤中,不到1%主要累及颅骨,其中蝶骨和颞骨是好发部位。在儿童年龄组中,骨巨细胞瘤极为罕见。

病例报告

作者报告了1例18个月大女孩额骨骨巨细胞瘤的治疗情况。患者接受了病变的广泛手术切除,治疗30个月后,临床和影像学检查均未发现肿瘤复发迹象。

结论

尽管罕见,但骨巨细胞瘤应作为小儿患者快速增大的颅骨肿块病变的鉴别诊断之一。手术全切可消除辅助放疗的潜在风险。然而,鉴于这些病变的侵袭性和潜在恶性,建议进行仔细的长期临床和影像学随访。

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