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枕骨巨细胞瘤:一例报告并文献复习

Giant cell tumor of the occipital bone: A case report and review of the literature.

作者信息

Uslu Gonca Hanedan, Canyilmaz Emine, Yöney Adnan, Aydin Sevdegül, Sahbaz Asli, Sari Ahmet

机构信息

Department of Radiation Oncology, Kanuni Research and Education Hospital, Trabzon 60080, Turkey.

Department of Radiation Oncology, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey.

出版信息

Oncol Lett. 2014 Jul;8(1):151-154. doi: 10.3892/ol.2014.2086. Epub 2014 Apr 25.

DOI:10.3892/ol.2014.2086
PMID:24959236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4063638/
Abstract

Giant cell tumors (GCTs) are usually found in the epiphysis of the long bones, and represent ~5% of all bone tumors. Only <1% of GCTs are localized in the cranium. When localized in the cranium, GCTs are commonly observed in the sphenoid or temporal bones, and rarely in the parietal or frontal bones. Occipital bone posterior fossa involvement is an extremely rare occurrence. The current study presents a 22-year-old female patient was admitted to the Department of Radiation Oncology (Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey) with complaints of neck pain and headache. The patients cranial magnetic resonance images showed a 2.5 6-cm mass in the occipital bone, which was subtotally excised. The patient was treated with radiotherapy following the surgery. At present, the patient has shown no progression after 20 months of follow-up.

摘要

骨巨细胞瘤(GCTs)通常发生于长骨的骨骺,约占所有骨肿瘤的5%。仅有不到1%的骨巨细胞瘤发生于颅骨。当发生于颅骨时,骨巨细胞瘤常见于蝶骨或颞骨,很少见于顶骨或额骨。枕骨后颅窝受累极为罕见。本研究报告了一名22岁女性患者,因颈部疼痛和头痛入住放射肿瘤学系(土耳其特拉布宗,黑海技术大学医学院)。患者的头颅磁共振成像显示枕骨有一个2.5×6厘米的肿块,该肿块被次全切除。术后患者接受了放射治疗。目前,患者在随访20个月后未出现病情进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a6/4063638/0c46f542f21c/OL-08-01-0151-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a6/4063638/ff6c2f2239fb/OL-08-01-0151-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a6/4063638/0c46f542f21c/OL-08-01-0151-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a6/4063638/ff6c2f2239fb/OL-08-01-0151-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a6/4063638/0c46f542f21c/OL-08-01-0151-g01.jpg

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本文引用的文献

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Intensity modulated radiotherapy (IMRT) in benign giant cell tumors--a single institution case series and a short review of the literature.调强放疗(IMRT)治疗良性骨巨细胞瘤的单中心病例系列研究及文献复习
Radiat Oncol. 2010 Feb 26;5:18. doi: 10.1186/1748-717X-5-18.
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Giant cell tumor of the frontal bone in an 18-month-old girl: a case report.18个月女童额骨巨细胞瘤:一例报告
枕骨基部出血性巨细胞瘤:病例报告及文献综述
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The identification of H3F3A mutation in giant cell tumour of the clivus and the histological diagnostic algorithm of other clival lesions permit the differential diagnosis in this location.岩斜坡巨细胞瘤中 H3F3A 突变的鉴定和其他岩斜坡病变的组织学诊断算法可实现该部位的鉴别诊断。
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RANK pathway in giant cell tumor of bone: pathogenesis and therapeutic aspects.骨巨细胞瘤中的RANK通路:发病机制与治疗方面
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