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[发病率压缩:缓解人口老龄化社会后果的一种有前景的方法?]

[Compression of morbidity: a promising approach to alleviate the societal consequences of population ageing?].

作者信息

Klijs B, Nusselder W J, Mackenbach J P

机构信息

Afdeling Maatschappelijke Gezondheidszorg, Erasmus MC, Rotterdam.

出版信息

Tijdschr Gerontol Geriatr. 2009 Dec;40(6):228-36. doi: 10.1007/BF03088516.

Abstract

There is an urgent need for strategies that alleviate the societal consequences of population ageing. A possible strategy is aiming for compression of morbidity. Some of the initial conditions for a compression of morbidity have been invalidated. This is, the life expectancy has shown a much stronger increase than was expected and the modal age at death has exceeded the age of 85. Additionally, trend studies have found no consistent evidence for a compression of morbidity. At the department of Public Health, we aim at identifying entry-points for a compression. For example, an analysis was performed on potential contributions of changes in exposure to life style factors (smoking, hypertension, physical inactivity and overweight/obesity) to compression of cardiovascular disease, using multi-state life tables with data from the Framingham Heart Study. It was shown that smoking and physical inactivity increased the incidence of cardiovascular disease, as well as mortality with and without cardiovascular disease. Hypertension and overweight mainly increased the incidence of cardiovascular disease and were associated with a shorter lifespan and more years with cardiovascular disease. Interventions on the latter risk factors will therefore increase the life expectancy, but will also result in a compression of morbidity. For policymakers and researchers it is important to find a mix of interventions that lead to a comparable overall effect.

摘要

迫切需要能减轻人口老龄化社会后果的策略。一种可能的策略是致力于压缩发病期。一些压缩发病期的初始条件已不再成立。也就是说,预期寿命的增长幅度远超预期,死亡的众数年龄已超过85岁。此外,趋势研究并未找到有关压缩发病期的一致证据。在公共卫生部门,我们旨在确定实现压缩发病期的切入点。例如,利用来自弗雷明汉心脏研究的数据的多状态生命表,对生活方式因素(吸烟、高血压、缺乏身体活动和超重/肥胖)暴露变化对心血管疾病压缩发病期的潜在贡献进行了分析。结果表明,吸烟和缺乏身体活动会增加心血管疾病的发病率,以及患心血管疾病和未患心血管疾病情况下的死亡率。高血压和超重主要增加心血管疾病的发病率,并与较短的寿命以及患心血管疾病的更多年数相关。因此,对后几种风险因素进行干预将提高预期寿命,但也会导致发病期的压缩。对于政策制定者和研究人员而言,找到能产生类似总体效果的干预措施组合非常重要。

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