Département d'Oncologie Radiothérapie, Unité fonctionnelle de Sénologie, Institut Gustave Roussy, Villejuif, France.
Radiat Oncol. 2010 Jan 14;5:2. doi: 10.1186/1748-717X-5-2.
Early breast cancer treatment is based on a multimodality approach with the application of clinical and histological prognostic factors to determine locoregional and systemic treatments. The entire scientific community is strongly involved in the management of this disease: radiologists for screening and early diagnosis, gynecologists, surgical oncologists and radiation oncologists for locoregional treatment, pathologists and biologists for personalized characterization, genetic counselors for BRCA mutation history and medical oncologists for systemic therapies.Recently, new biological tools have established various prognostic subsets of breast cancer and developed predictive markers for miscellaneous treatments.The aim of this article is to highlight the contribution of biological tools in the locoregional management of early breast cancer.
早期乳腺癌的治疗基于多模式方法，应用临床和组织学预后因素来确定局部和全身治疗。整个科学界都积极参与这种疾病的管理：放射科医生进行筛查和早期诊断，妇科医生、外科肿瘤学家和放射肿瘤学家进行局部区域治疗，病理学家和生物学家进行个性化特征分析，遗传咨询师进行 BRCA 突变史分析，肿瘤内科医生进行全身治疗。最近，新的生物学工具已经确定了乳腺癌的各种预后亚组，并为各种治疗方法开发了预测标志物。本文的目的是强调生物学工具在早期乳腺癌的局部区域管理中的贡献。
