Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):867-78. doi: 10.1177/039463200902200402.
This update on treatment of asthma exacerbations in children is the result of an Italian Pediatric Society Task-force, made up of a panel of experts working in 2007-2008. The aim is to give clear indications on the use of the drugs most employed in children, grading the quality of evidence and the strength of recommendations. Suggestions on their limits due to unlicensed and off-label use are reported. The level of evidence and the strength of recommendations for different therapeutic approaches demonstrate that frequently the use of drugs in children is extrapolated from the experience in adults and that more studies are required to endorse the correct use of different drugs in asthmatic children.
这是意大利儿科学会专家组在 2007 年至 2008 年期间开展工作的成果，更新了儿童哮喘加重的治疗内容。目的是为最常用于儿童的药物使用提供明确的指导，对证据质量和推荐强度进行分级。报告了由于未授权和超适应证使用而产生的限制。不同治疗方法的证据水平和推荐强度表明，儿童药物的使用通常是从成人经验推断出来的，需要更多的研究来支持不同药物在哮喘儿童中的正确使用。
