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对曾有过非甾体抗炎药反应的患者使用依托考昔的长期耐受性。

Long-term tolerability of etoricoxib in patients with previous reactions to non-steroidal anti-inflammatory drugs.

出版信息

Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):1131-4. doi: 10.1177/039463200902200431.

Abstract

Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that etoricoxib shows a high long-term tolerability in patients with non-steroidal anti-inflammatory drug hypersensitivity.

摘要

非甾体抗炎药经常会引起不良反应。本回顾性研究基于对 173 名接受并耐受依托考昔(一种选择性环氧化酶-2 酶抑制剂)挑战试验患者的访谈数据进行分析。在接受依托考昔治疗的 82 名患者中仅有 1 例报告有反应。我们可以得出结论,依托考昔在非甾体抗炎药过敏患者中具有较高的长期耐受性。

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