Reproductive Endocrinology and Infertility, Department of Gynecology-Obstetrics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Fertil Steril. 2010 Aug;94(3):1129-31. doi: 10.1016/j.fertnstert.2009.11.007. Epub 2010 Jan 13.
In severe forms of Diamond-Blackfan anemia, preimplantation genetic diagnosis (PGD) of histocompatibility leukocyte antigen-compatible embryos for enabling the next sibling in the family to be a stem-cell transplantation donor constitutes the sole lasting cure capable of terminating the enduring need for iterative transfusions. We report here an open collaboration between two renowned institutions to provide a family desiring this treatment even though they resided where the preimplantation genetic diagnosis procedure is banned.
在严重的 Diamond-Blackfan 贫血症中，为了使家族中的下一个兄弟姐妹能够成为干细胞移植供体，对组织相容性白细胞抗原相容的胚胎进行着床前遗传学诊断（PGD）是唯一能够持久治愈并终止反复输血需求的方法。我们在此报告了两个知名机构之间的公开合作，为一个有此治疗需求的家庭提供了帮助，尽管他们居住的地方禁止进行着床前遗传学诊断程序。
