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[先天性颗粒细胞瘤的产前诊断]

[Antenatal diagnosis of a congenital granular cell tumor].

作者信息

Abbo O, Breibach F, Vaysse F, Kessler S, Guitard J, Galinier P

机构信息

Service de chirurgie viscérale, hôpital des Enfants de Toulouse, 330, avenue de Grande-Bretagne, TSA 70034, 31059 Toulouse cedex 9, France.

出版信息

Rev Stomatol Chir Maxillofac. 2010 Apr;111(2):91-3. doi: 10.1016/j.stomax.2009.07.010. Epub 2010 Jan 13.

Abstract

INTRODUCTION

Neuman's tumors also called congenital epulis or congenital gingival granulomatous tumors are rare and benign oral cavity tumors. They are usually discovered at birth.

CASE REPORT

A 32 year-old pregnant female patient was followed for gravid diabetes well controlled. A maxillary tumor in the fetus was revealed by the third trimester US. A fetal MRI was prescribed, after discussion with the antenatal diagnostic center, to determine the localization, size, and nature of the tumor. It revealed a 3 cm long tumor with cystic like areas not communicating with the encephalus. A caesarian section was performed 2 weeks before term. A simple tumoral excision was performed at 12 hours of age. Histological analysis confirmed the diagnosis. There was no local recurrence after 6 months of follow-up.

DISCUSSION

A prenatal diagnosis of congenital gingival granulomatous tumor is rare. It is usually made at the third trimester ultrasound scan, rarely with fetal MRI. Nevertheless, prenatal diagnosis allows for a better postnatal management.

摘要

引言

纽曼氏肿瘤也称为先天性龈瘤或先天性牙龈肉芽肿性肿瘤,是罕见的良性口腔肿瘤。它们通常在出生时被发现。

病例报告

一名32岁的妊娠女性患者因妊娠糖尿病得到良好控制而接受随访。孕晚期超声检查发现胎儿上颌有肿瘤。在与产前诊断中心讨论后,进行了胎儿磁共振成像检查,以确定肿瘤的位置、大小和性质。检查发现一个3厘米长的肿瘤,有类似囊肿的区域,与脑不连通。在预产期前2周进行了剖宫产。在婴儿出生12小时时进行了简单的肿瘤切除。组织学分析证实了诊断。随访6个月后无局部复发。

讨论

先天性牙龈肉芽肿性肿瘤的产前诊断很少见。通常在孕晚期超声检查时发现,很少通过胎儿磁共振成像。然而,产前诊断有助于更好地进行产后管理。

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