Department of Microbiology, Auckland City Hospital, Private Bag 92024, Grafton, Auckland 1023, New Zealand.
J Clin Neurosci. 2010 Mar;17(3):296-8. doi: 10.1016/j.jocn.2009.06.016. Epub 2010 Jan 13.
We prospectively compared the incidence of ventriculitis associated with external ventricular drains (EVD) impregnated with clindamycin and rifampicin with historical controls. We found the use of antibiotic impregnated (AI) EVDs showed a significant decrease in positive cerebrospinal fluid cultures and a significant delay in time to EVD infection.
我们前瞻性地比较了包被克林霉素和利福平的外引流管(EVD)与历史对照的脑室炎发生率。我们发现使用抗生素包被(AI)的 EVD 可显著降低脑脊液培养阳性率,并显著延迟 EVD 感染的时间。