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印度南部泰米尔纳德邦基于人群的糖尿病视网膜病变患病率及危险因素分析。

Prevalence and risk factors for diabetic retinopathy: a population-based assessment from Theni District, south India.

机构信息

Retina Vitreous Services, Aravind Eye Hospital, Anna Nagar, Madurai 625020, India.

出版信息

Postgrad Med J. 2009 Dec;85(1010):643-8. doi: 10.1136/bjo.2008.147934.

Abstract

AIMS

To estimate the prevalence of diabetic retinopathy (DR) and the possible risk factors associated with DR, in a population of south India.

METHODS

A cross-sectional sample of subjects aged 30 years and older was selected using a cluster sampling technique from Theni district of Tamilnadu state. Eligible subjects were identified through a door-to-door survey and fasting blood glucose estimation. History of diabetes was elicited, and height, weight and blood pressure were measured for all subjects. Ocular examinations including visual acuity and anterior and posterior segment examinations were performed at preselected sites within clusters.

RESULTS

Among the 25 969 persons screened for diabetes mellitus (DM), 2802 (10.8%) (95% CI 9.3 to 12.2%) were found to have DM. DR was detected in 298 (1.2%) of 25 969 subjects. The age-gender-adjusted prevalence of DR is 0.05% (95% CI 0.04 to 0.06%) for rural and 1.03% (95% CI 0.89 to 1.12%) for urban areas. The overall age-gender-cluster adjusted prevalence of DR was 0.74% (95% CI 0.66 to 0.83%). Diabetic retinopathy was present in 12.2% (95% CI 10.4 to 14.1%) of the DM population.

CONCLUSION

Adequate training of ophthalmologists in treating DR and improvement in eye-care infrastructure are needed to tackle this major public health problem in India.

摘要

目的

评估印度南部人群中糖尿病视网膜病变(DR)的患病率和可能与 DR 相关的危险因素。

方法

采用聚类抽样技术,从泰米尔纳德邦的蒂尼区选择了 30 岁及以上的横断面样本。通过挨家挨户调查和空腹血糖估计,确定符合条件的受试者。对所有受试者进行了糖尿病史的询问,并测量了身高、体重和血压。在聚类内的预选地点进行了眼部检查,包括视力和眼前段及后段检查。

结果

在筛查的 25969 名糖尿病患者(DM)中,发现 2802 名(10.8%)(95%CI 9.3%至 12.2%)患有 DM。在 25969 名受试者中,发现 298 名(1.2%)患有 DR。DR 的年龄-性别调整患病率为农村地区 0.05%(95%CI 0.04%至 0.06%),城市地区 1.03%(95%CI 0.89%至 1.12%)。总体年龄-性别-聚类调整的 DR 患病率为 0.74%(95%CI 0.66%至 0.83%)。DR 存在于 12.2%(95%CI 10.4%至 14.1%)的 DM 人群中。

结论

需要对眼科医生进行充分的 DR 治疗培训,并改善眼保健基础设施,以解决印度这一主要公共卫生问题。

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