Risk Assessment Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea.
J Toxicol Environ Health A. 2009;72(21-22):1336-42. doi: 10.1080/15287390903212485.
Oriental medical herbs are mainly natural products that are generated by simple processes, and therefore there is the possibility of contamination with various pollutants, including heavy metals. Heavy metals produce adverse effects in humans, and the toxicities of lead (Pb) and cadmium (Cd) are well established. This study evaluated the effects of exposure to Pb and Cd via the intake of the frequent prescriptions of oriental medicines, and assessed the risk to the Korean population based on domestic data. The average daily exposures to Pb and Cd were estimated. This is the first study to evaluate exposure and risk of heavy metal intoxication through intake of oriental medicines in Korea. Despite the uncertainties and limits of the data, these results simulate realistic exposure levels.
东方草药主要是天然产物，其生产过程简单，因此有可能受到各种污染物的污染，包括重金属。重金属会对人类产生不良影响，铅（Pb）和镉（Cd）的毒性已得到充分证实。本研究通过摄入常见的东方药物来评估通过摄入 Pb 和 Cd 的暴露情况，并根据国内数据评估对韩国人群的风险。估计了 Pb 和 Cd 的平均日摄入量。这是第一项评估通过摄入东方药物导致韩国重金属中毒的暴露和风险的研究。尽管数据存在不确定性和局限性，但这些结果模拟了现实的暴露水平。
