Tanaka S, Pollock B E
Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Minim Invasive Neurosurg. 2009 Oct;52(5-6):259-62. doi: 10.1055/s-0029-1243242. Epub 2010 Jan 14.
Preservation of cranial nerve function is critical in the management of patients with cerebellopontine angle (CPA) tumors.
A 51-year-old woman with tinnitus and dizziness was discovered to have bilateral CPA dural-based masses extending into the internal auditory canals (IAC). Pre-operatively, the patient had normal hearing on the right (SRT, 5 dB; SDS 100% at 30 dB) and left (SRT, 10 dB; SDS 90% at 40 dB). The patient underwent two Leksell Gamma Knife (Elekta Instruments, Norcross, GA) radiosurgeries initially for the larger left-sided tumor, then one year later for the right. The margin dose for each tumor was 14 Gy. Six years after the first radiosurgery, the tumors have not progressed and she has retained normal hearing and facial function bilaterally.
Preservation of cranial nerve function is generally possible after stereotactic radiosurgery of CPA meningiomas.
保留颅神经功能在桥小脑角（CPA）肿瘤患者的治疗中至关重要。
一名51岁患有耳鸣和头晕的女性被发现双侧CPA有硬膜下肿块延伸至内耳道（IAC）。术前，患者右侧听力正常（言语识别阈，5分贝；30分贝时言语辨别得分100%），左侧听力正常（言语识别阈，10分贝；40分贝时言语辨别得分90%）。患者最初接受了两次Leksell伽玛刀（Elekta仪器公司，佐治亚州诺克罗斯）放射外科手术，第一次针对较大的左侧肿瘤，一年后针对右侧肿瘤。每个肿瘤的边缘剂量为14 Gy。第一次放射外科手术后六年，肿瘤未进展，她双侧听力和面部功能均保持正常。
CPA脑膜瘤立体定向放射外科手术后通常可以保留颅神经功能。
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