Yang Zhao-Hui, Yin Shao-Fu, Zhang Zong-Jiu
State Key Laboratory for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhongguo Yi Miao He Mian Yi. 2009 Feb;15(1):72-7.
Coxsackievirus A group 16 strain (CVA16) is one of the predominate causative agent of the hand, foot and mouth disease (HFHD). It is very helpful to improve the hand, foot and mouth disease and other associated diseases control and prevention by understanding its biological characteristics, pathogenic mechanism and clinical manifestations, laboratory diagnoses, epidemiology and molecular epidemiology. In the future, we should continue to emphasize the study, improve the diagnostic method and develop vaccine of CVA16. A sound monitoring network of both epidemiology and laboratory will be estabished as well, which can contribute to predicting and prewarning the epidemic conditions of CVA16, and is much important scientific tools for preventing the hand, foot and mouth disease associated with CVA16.
肠道病毒A16型（CVA16）是手足口病（HFHD）的主要致病原之一。了解其生物学特性、致病机制、临床表现、实验室诊断、流行病学及分子流行病学，对提高手足口病及其他相关疾病的防控水平具有重要意义。未来应继续加强对CVA16的研究，完善诊断方法，研发疫苗。同时，建立健全流行病学和实验室监测网络，有助于对CVA16疫情进行预测预警，是防控CVA16相关手足口病的重要科学手段。
