Harada Shohei
Department of Health Policy, National Center for Child Health and Development.
Nihon Rinsho. 2010 Jan;68(1):127-30.
Since the nation-wide neonatal screening programs for congenital hypothyroidism(CH) had been implemented in 1979, the diagnosis and treatment of CH are now provided in the first 2-3 weeks of birth in Japan. The goals of treatment are to raise the serum T4 as rapidly as possible into the normal range, and maintain normal growth and development while avoiding overtreatment. Because transient hypothyroidism may occur frequently, a reevaluation after 3 years is needed in such patients. Patients with CH had normal growth in general, suggesting that the neonatal screening system is being performed efficiently from detection to treatment of the disease in Japan. Pediatric and adult thyroidologists are engaging in processes to promote the continuity of care for patients with CH.
自1979年日本实施全国先天性甲状腺功能减退症（CH）新生儿筛查项目以来，目前在日本，CH的诊断和治疗在出生后的头2至3周内即可进行。治疗目标是尽快将血清T4提升至正常范围，并维持正常的生长发育，同时避免过度治疗。由于短暂性甲状腺功能减退症可能经常发生，此类患者需要在3年后进行重新评估。CH患者总体生长正常，这表明日本的新生儿筛查系统在该疾病从检测到治疗的过程中运行高效。儿科和成人甲状腺专家正在努力促进对CH患者护理的连续性。
