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新西兰美沙酮维持治疗项目中患者的药物注射:一项匿名调查。

Drug injecting in patients in New Zealand Methadone Maintenance Treatment programs: an anonymous survey.

机构信息

Taranaki Alcohol and Drug Service, Taranaki, New Zealand.

出版信息

Drug Alcohol Rev. 2010 Jan;29(1):41-6. doi: 10.1111/j.1465-3362.2009.00080.x.

Abstract

INTRODUCTION AND AIMS

To investigate the prevalence and nature of injecting behaviour among patients on Methadone Maintenance Treatment (MMT) programs.

DESIGN AND METHODS

A self-reported questionnaire was handed to 423 patients enrolled in MMT across six clinics in the lower North Island of New Zealand.

RESULTS

A total of 151 patients responded, giving a 35.6% response rate. One hundred and twenty (79.5%) respondents reported they had injected methadone while enrolled in MMT, 84 (55.6%) had injected methadone in the last year and of those 43 (35.8%) had injected methadone in the last week. Reasons given for injecting of methadone included: rapid onset of effect, needle fixation and euphoria. Time on the methadone programme was negatively associated with ever injecting methadone [odds ratio (95% CI) 0.92 (0.85-0.99), P = 0.029] and injecting other substances [odds ratio (95% CI) 0.93(0.87-1.0), P = 0.046]. More frequent pharmacy-observed consumption was associated with increased injecting of other substances [odds ratio (95% CI) 1.32 (1.09-1.59), P = 0.005] but not methadone. The time a person had been enrolled on the methadone programme was associated with decreased use of other substances [odds ratio (95% CI) 0.93 (0.87-1.0), P = 0.046].

DISCUSSION AND CONCLUSIONS

Many individuals on MMT continue to inject their methadone. In this sample, the frequency of injection of methadone did not correlate with prescribed dose or takeaway arrangements. The beneficial impact of time on the programme emphasises the importance of retention in treatment. It is suggested that these results also indicate a need for routine education concerning safe injecting.

摘要

介绍和目的

调查美沙酮维持治疗(MMT)计划中的患者注射行为的流行率和性质。

设计和方法

在新西兰北岛下游的六个诊所中,向 423 名参加 MMT 的患者发放了一份自我报告问卷。

结果

共有 151 名患者做出了回应,回应率为 35.6%。120 名(79.5%)受访者报告说,他们在参加 MMT 期间曾注射过美沙酮,84 名(55.6%)在过去一年中注射过美沙酮,其中 43 名(35.8%)在过去一周中注射过美沙酮。注射美沙酮的原因包括:快速起效、固定针头和欣快。在美沙酮治疗计划中的时间与曾经注射美沙酮呈负相关[比值比(95%可信区间)0.92(0.85-0.99),P=0.029]和注射其他物质[比值比(95%可信区间)0.93(0.87-1.0),P=0.046]。更频繁的药房观察性消费与其他物质的注射增加有关[比值比(95%可信区间)1.32(1.09-1.59),P=0.005],但与美沙酮无关。一个人参加美沙酮治疗计划的时间与其他物质的使用减少有关[比值比(95%可信区间)0.93(0.87-1.0),P=0.046]。

讨论和结论

许多参加 MMT 的人继续注射他们的美沙酮。在这个样本中,注射美沙酮的频率与规定的剂量或带走安排无关。在该计划中时间的有益影响强调了保留治疗的重要性。这表明这些结果还表明需要对安全注射进行常规教育。

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